Natural history of highly pathogenic avian influenza H5N1

• Published in: Virus research Vol. 178; no. 1; pp. 63 - 77
• Main Authors: Sonnberg, Stephanie, Webby, Richard J., Webster, Robert G.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 05.12.2013
• Subjects: Animals; avian influenza; Birds; China; Clade; Disease Outbreaks - history; disease reservoirs; ecology; genotype; History, 20th Century; History, 21st Century; hosts; humans; Influenza A virus; Influenza A Virus, H5N1 Subtype - genetics; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza A Virus, H5N1 Subtype - physiology; Influenza in Birds - epidemiology; Influenza in Birds - history; Influenza in Birds - transmission; Influenza in Birds - virology; Lineage; mutation; natural history; natural selection; poultry; Reservoir; risk; Virus evolution; viruses; waterfowl; Wild bird; China; Lineage; Virus evolution; Reservoir; Clade; Wild bird

•The ecology of highly pathogenic (HP) H5N1 is diverse, specific to strain and to host species.•Over time Asian HP H5N1 viruses have expanded their host range from geese to poultry.•Mutation and reassortment have given rise to multiple virus lineages.•Asian HP H5N1 has utilized wild waterfowl in lon...