Biological research on drug abuse and addiction in Hispanics: Current status and future directions

Impressive progress has been made in the understanding of biological contributions to drug abuse and addiction. An area that has only recently begun to receive attention is potential ethnic and racial differences in biological systems that contribute to, or protect from, problem drug use. This artic...

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Published inDrug and alcohol dependence Vol. 84; no. supplement 1; pp. S17 - S28
Main Authors Trujillo, Keith A., Castañeda, Edward, Martínez, Diana, González, Gerardo
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.09.2006
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ISSN0376-8716
1879-0046
DOI10.1016/j.drugalcdep.2006.05.004

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Abstract Impressive progress has been made in the understanding of biological contributions to drug abuse and addiction. An area that has only recently begun to receive attention is potential ethnic and racial differences in biological systems that contribute to, or protect from, problem drug use. This article reviews recent research on drug abuse and addiction in Hispanics in which biological questions have been addressed, including work on genes, gene products (proteins), physiology and pharmacotherapy. Taken together, work to date suggests that there are both similarities and differences between Hispanics and other ethnic groups in biological factors related to drug abuse and addiction. Although the results are intriguing, relatively few studies have been done, and those that have been done have often been inconclusive due to low numbers of Hispanic subjects. Moreover, studies have often failed to recognize the complexity and heterogeneity of Hispanic populations in the United States and around the world. After reviewing the current status of the field, recommendations are given for future research in both humans and relevant animal models that will lead to a better understanding of drug abuse and addiction in Hispanics.
AbstractList Impressive progress has been made in the understanding of biological contributions to drug abuse and addiction. An area that has only recently begun to receive attention is potential ethnic and racial differences in biological systems that contribute to, or protect from, problem drug use. This article reviews recent research on drug abuse and addiction in Hispanics in which biological questions have been addressed, including work on genes, gene products (proteins), physiology and pharmacotherapy. Taken together, work to date suggests that there are both similarities and differences between Hispanics and other ethnic groups in biological factors related to drug abuse and addiction. Although the results are intriguing, relatively few studies have been done, and those that have been done have often been inconclusive due to low numbers of Hispanic subjects. Moreover, studies have often failed to recognize the complexity and heterogeneity of Hispanic populations in the United States and around the world. After reviewing the current status of the field, recommendations are given for future research in both humans and relevant animal models that will lead to a better understanding of drug abuse and addiction in Hispanics.Impressive progress has been made in the understanding of biological contributions to drug abuse and addiction. An area that has only recently begun to receive attention is potential ethnic and racial differences in biological systems that contribute to, or protect from, problem drug use. This article reviews recent research on drug abuse and addiction in Hispanics in which biological questions have been addressed, including work on genes, gene products (proteins), physiology and pharmacotherapy. Taken together, work to date suggests that there are both similarities and differences between Hispanics and other ethnic groups in biological factors related to drug abuse and addiction. Although the results are intriguing, relatively few studies have been done, and those that have been done have often been inconclusive due to low numbers of Hispanic subjects. Moreover, studies have often failed to recognize the complexity and heterogeneity of Hispanic populations in the United States and around the world. After reviewing the current status of the field, recommendations are given for future research in both humans and relevant animal models that will lead to a better understanding of drug abuse and addiction in Hispanics.
Impressive progress has been made in the understanding of biological contributions to drug abuse and addiction. An area that has only recently begun to receive attention is potential ethnic and racial differences in biological systems that contribute to, or protect from, problem drug use. This article reviews recent research on drug abuse and addiction in Hispanics in which biological questions have been addressed, including work on genes, gene products (proteins), physiology and pharmacotherapy. Taken together, work to date suggests that there are both similarities and differences between Hispanics and other ethnic groups in biological factors related to drug abuse and addiction. Although the results are intriguing, relatively few studies have been done, and those that have been done have often been inconclusive due to low numbers of Hispanic subjects. Moreover, studies have often failed to recognize the complexity and heterogeneity of Hispanic populations in the United States and around the world. After reviewing the current status of the field, recommendations are given for future research in both humans and relevant animal models that will lead to a better understanding of drug abuse and addiction in Hispanics.
Impressive progress has been made in the understanding of biological contributions to drug abuse & addiction. An area that has only recently begun to receive attention is potential ethnic & racial differences in biological systems that contribute to, or protect from, problem drug use. This article reviews recent research on drug abuse & addiction in Hispanics in which biological questions have been addressed, including work on genes, gene products (proteins), physiology & pharmacotherapy. Taken together, work to date suggests that there are both similarities & differences between Hispanics & other ethnic groups in biological factors related to drug abuse & addiction. Although the results are intriguing, relatively few studies have been done, & those that have been done have often been inconclusive due to low numbers of Hispanic subjects. Moreover, studies have often failed to recognize the complexity & heterogeneity of Hispanic populations in the United States & around the world. After reviewing the current status of the field, recommendations are given for future research in both humans & relevant animal models that will lead to a better understanding of drug abuse & addiction in Hispanics. Tables, References. [Copyright 2006 Elsevier Ireland Ltd.]
Author González, Gerardo
Martínez, Diana
Trujillo, Keith A.
Castañeda, Edward
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Keywords Ethnicity
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Neurobiology
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Snippet Impressive progress has been made in the understanding of biological contributions to drug abuse and addiction. An area that has only recently begun to receive...
Impressive progress has been made in the understanding of biological contributions to drug abuse & addiction. An area that has only recently begun to receive...
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SubjectTerms Aldehyde Dehydrogenase - metabolism
Biology - methods
Biology - trends
Brain - metabolism
Carcinogens, Environmental - adverse effects
Dopamine - metabolism
Drug abuse
Drug addiction
Environment
Ethnicity
Forecasting
Gene Expression - genetics
Hispanic Americans - statistics & numerical data
Hispanic people
Hispanics
Humans
N-Methylaspartate - metabolism
Neurobiological aspects
Neurobiology
Norepinephrine - metabolism
Nutritional Status
Prevalence
Receptors, GABA-A - metabolism
Research - trends
Research Design
Serotonin - metabolism
Socioeconomic Factors
Substance-Related Disorders - ethnology
Substance-Related Disorders - genetics
Substance-Related Disorders - metabolism
Title Biological research on drug abuse and addiction in Hispanics: Current status and future directions
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0376871606001694
https://dx.doi.org/10.1016/j.drugalcdep.2006.05.004
https://www.ncbi.nlm.nih.gov/pubmed/16777354
https://www.proquest.com/docview/20404346
https://www.proquest.com/docview/57078272
https://www.proquest.com/docview/68718947
Volume 84
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