Evolution of the CYP2ABFGST gene cluster in rat, and a fine-scale comparison among rodent and primate species
The evolution of gene families can be best understood by studying the modern organization and functions of family members, and by comparing parallel families in different species. In this study, the CYP2ABFGST gene cluster has been characterized in rat and compared to the syntenic clusters in mouse...
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Published in | Genetica Vol. 133; no. 2; pp. 215 - 226 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
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Dordrecht
Dordrecht : Springer Netherlands
01.06.2008
Springer Netherlands Springer Nature B.V |
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Abstract | The evolution of gene families can be best understood by studying the modern organization and functions of family members, and by comparing parallel families in different species. In this study, the CYP2ABFGST gene cluster has been characterized in rat and compared to the syntenic clusters in mouse and human, providing an interesting example of gene family evolution. In the rat, 18 loci from six subfamilies have been identified by specifically amplifying and sequencing gene fragments from cloned DNA, and have been exactly placed on chromosome 1. The overall organization of the gene cluster in rat is relatively simple, with genes from each subfamily in tandem, and is more similar to the mouse than to the human cluster. We have reconstructed the probable structure of the CYP2ABFGST cluster in the common ancestor of primates and rodents, and inferred a model of the evolution of this gene cluster in the three species. Numerous nontandem and block duplications, inversions, and translocations have occurred entirely inside the cluster, indicating that pairing between duplicate genes is keeping the rearrangements within the cluster region. The initial tandem duplication of a CYP2 gene in an early mammalian ancestor has made this region particularly subject to such localized rearrangements. Even if duplicated genes do not have a large-scale effect on chromosomal rearrangements, on a local level clustered gene families may have contributed significantly to the genomic complexity of modern mammals. |
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AbstractList | The evolution of gene families can be best understood by studying the modern organization and functions of family members, and by comparing parallel families in different species. In this study, the CYP2ABFGST gene cluster has been characterized in rat and compared to the syntenic clusters in mouse and human, providing an interesting example of gene family evolution. In the rat, 18 loci from six subfamilies have been identified by specifically amplifying and sequencing gene fragments from cloned DNA, and have been exactly placed on chromosome 1. The overall organization of the gene cluster in rat is relatively simple, with genes from each subfamily in tandem, and is more similar to the mouse than to the human cluster. We have reconstructed the probable structure of the CYP2ABFGST cluster in the common ancestor of primates and rodents, and inferred a model of the evolution of this gene cluster in the three species. Numerous nontandem and block duplications, inversions, and translocations have occurred entirely inside the cluster, indicating that pairing between duplicate genes is keeping the rearrangements within the cluster region. The initial tandem duplication of a CYP2 gene in an early mammalian ancestor has made this region particularly subject to such localized rearrangements. Even if duplicated genes do not have a large-scale effect on chromosomal rearrangements, on a local level clustered gene families may have contributed significantly to the genomic complexity of modern mammals. The evolution of gene families can be best understood by studying the modern organization and functions of family members, and by comparing parallel families in different species. In this study, the CYP2ABFGST gene cluster has been characterized in rat and compared to the syntenic clusters in mouse and human, providing an interesting example of gene family evolution. In the rat, 18 loci from six subfamilies have been identified by specifically amplifying and sequencing gene fragments from cloned DNA, and have been exactly placed on chromosome 1. The overall organization of the gene cluster in rat is relatively simple, with genes from each subfamily in tandem, and is more similar to the mouse than to the human cluster. We have reconstructed the probable structure of the CYP2ABFGST cluster in the common ancestor of primates and rodents, and inferred a model of the evolution of this gene cluster in the three species. Numerous nontandem and block duplications, inversions, and translocations have occurred entirely inside the cluster, indicating that pairing between duplicate genes is keeping the rearrangements within the cluster region. The initial tandem duplication of a CYP2 gene in an early mammalian ancestor has made this region particularly subject to such localized rearrangements. Even if duplicated genes do not have a large-scale effect on chromosomal rearrangements, on a local level clustered gene families may have contributed significantly to the genomic complexity of modern mammals. |
Author | Wang, Haoyi Reddy, Shanti Knisely, Alyssa A Hoffman, Susan M. G Liu, Zhi Hu, Shengyong Kovacevic, David |
Author_xml | – sequence: 1 fullname: Hu, Shengyong – sequence: 2 fullname: Wang, Haoyi – sequence: 3 fullname: Knisely, Alyssa A – sequence: 4 fullname: Reddy, Shanti – sequence: 5 fullname: Kovacevic, David – sequence: 6 fullname: Liu, Zhi – sequence: 7 fullname: Hoffman, Susan M. G |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/17876710$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/S0140-6736(02)11203-7 10.1097/00008571-199602000-00002 10.1007/s00239-003-0028-x 10.1093/carcin/22.1.155 10.1021/bi00435a026 10.1097/00008571-200401000-00001 10.1369/jhc.4C6576.2005 10.1016/j.taap.2003.09.020 10.1016/S1055-7903(03)00079-4 10.1124/jpet.104.075440 10.1007/BF00171816 10.1089/dna.1994.13.781 10.1007/s00239-005-0134-z 10.1073/pnas.80.13.3958 10.1074/jbc.273.15.9279 10.1006/abbi.1997.9899 10.1016/0006-2952(96)00411-X 10.1124/mol.61.2.255 10.1126/science.1107808 10.1097/00008571-200111000-00007 10.1007/PL00006562 10.1186/gb-2000-1-6-reviews3003 10.1016/S1383-5742(97)00040-9 10.1016/S0021-9258(18)83497-4 10.1289/ehp.6546 10.1089/dna.1987.6.1 10.1089/dna.1993.12.1 10.1016/j.mrfmmm.2006.11.004 10.1016/S0021-9258(18)61575-3 10.1016/S0021-9258(17)39550-9 10.1016/S0027-5107(01)00274-3 |
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References | Lewis, Watson, Lake (CR19) 1998; 410 Jean, Reiss, Desrochers, Dubois, Trottier, Trottier (CR14) 1994; 13 Nebert, Adesnik, Coon, Estabrook, Gonzalez, Guengerich, Gunsalus, Johnson, Kemper, Levin, Phillips, Sato, Waterman (CR23) 1987; 6 Chen, Whitehead, Caillat, Gavit, Isphording, Kovacevic, McCreary, Hoffman (CR5) 2002; 499 Nelson, Koymans, Kamataki, Stegeman, Feyereisen, Waxman, Waterman, Gotoh, Coon, Estabrook, Gunsalus, Nebert (CR28) 1996; 6 Hua, Zhang, Su, Lipinskas, Ding (CR13) 1997; 340 Asher, Meng, Wible, McKenna, Rougier, Dashzeveg, Novacek (CR2) 2005; 307 Goldstone, Stegeman (CR9) 2006; 62 O’hUigin, Li (CR30) 1992; 35 Werck-Reichhart, Feyereisen (CR36) 2000; 1 Du, Hoffman, Keeney (CR7) 2004; 195 Kimura, Kozak, Gonzalez (CR16) 1989; 28 Nagata, Matsunaga, Gillette, Gelboin, Gonzalez (CR22) 1987; 262 Wang, Donley, Keeney, Hoffman (CR35) 2003; 111 Rivera, Saarikoski, Hankinson (CR31) 2002; 61 Lee (CR18) 1999; 49 Misawa, Janke (CR20) 2003; 2 Aoyama, Korzekwa, Matsunaga, Nagata, Gillette, Gelboin (CR1) 1990; 18 Saarikoski, Wikman, Smith, Wolff, Husgafvel-Pursiainen (CR40) 2005; 53 Brookman-Amissah, Mackay, Mace, Swann (CR4) 2001; 22 Trottier, Dubois, Jean, Anderson (CR34) 1996; 52 Suwa, Mizukami, Sogawa, Fujii-Kuriyama (CR33) 1985; 260 Hoffman, Nelson, Keeney (CR12) 2001; 11 CR26 Nelson, Kamataki, Waxman, Guengerich, Estabrook, Feyereisen, Gonzalez, Coon, Gunsalus, Gotoh, Okuda, Nebert (CR27) 1993; 12 Nelson, Zeldin, Hoffman, Maltais, Wain, Nebert (CR29) 2004; 14 Mizukami, Sogawa, Suwa, Muramatsu, Fujii-Kuriyama (CR21) 1983; 80 Lanza, Code, Crespi, Gonzalez, Yost (CR17) 1999; 27 Hoffman, Hu (CR11) 2007; 616 Nebert, Russell (CR24) 2002; 360 Baldwin, Shultz, Buckpitt (CR3) 2005; 312 Keeney, Skinner, Wei, Friedberg, Waterman (CR15) 1998; 273 Nef, Heldman, Lazard, Margalit, Jaye, Hanukoglu (CR25) 1989; 264 Fernandez-Salguero, Hoffman, Cholerton, Mohrenweiser, Raunio, Pelkonen (CR8) 1995; 57 Shultz, Choudary, Buckpitt (CR32) 1999; 290 Hoffman, Fernandez-Salguero, Mohrenweiser, Gonzalez (CR10) 1995; 41 Douzery, Delsuc, Stanhope, Huchon (CR6) 2003; 57 9535921 - J Biol Chem. 1998 Apr 10;273(15):9279-84 8845856 - Pharmacogenetics. 1996 Feb;6(1):1-42 2989270 - J Biol Chem. 1985 Jul 5;260(13):7980-4 8068203 - DNA Cell Biol. 1994 Aug;13(8):781-92 15020190 - Toxicol Appl Pharmacol. 2004 Mar 15;195(3):278-87 11159754 - Carcinogenesis. 2001 Jan;22(1):155-60 3829886 - DNA. 1987 Feb;6(1):1-11 11809848 - Mol Pharmacol. 2002 Feb;61(2):255-9 10473780 - J Mol Evol. 1999 Sep;49(3):385-91 1974203 - Drug Metab Dispos. 1990 May-Jun;18(3):378-82 3818621 - J Biol Chem. 1987 Feb 25;262(6):2787-93 11827709 - Mutat Res. 2002 Feb 20;499(2):155-61 15718468 - Science. 2005 Feb 18;307(5712):1091-4 8587134 - J Mol Evol. 1995 Dec;41(6):894-900 12387968 - Lancet. 2002 Oct 12;360(9340):1155-62 14630516 - Environ Health Perspect. 2003 Nov;111(15):1835-42 16752211 - J Mol Evol. 2006 Jun;62(6):708-17 2708343 - J Biol Chem. 1989 Apr 25;264(12):6780-5 15872048 - J Histochem Cytochem. 2005 May;53(5):549-56 12878468 - Mol Phylogenet Evol. 2003 Aug;28(2):320-7 7678494 - DNA Cell Biol. 1993 Jan-Feb;12(1):1-51 15008417 - J Mol Evol. 2003;57 Suppl 1:S201-13 11692077 - Pharmacogenetics. 2001 Nov;11(8):687-98 9630657 - Mutat Res. 1998 Jun;410(3):245-70 17194463 - Mutat Res. 2007 Mar 1;616(1-2):133-8 8781517 - Biochem Pharmacol. 1996 Sep 27;52(6):963-5 11178272 - Genome Biol. 2000;1(6):REVIEWS3003 15128046 - Pharmacogenetics. 2004 Jan;14(1):1-18 7668294 - Am J Hum Genet. 1995 Sep;57(3):651-60 15509722 - J Pharmacol Exp Ther. 2005 Feb;312(2):857-65 10381788 - J Pharmacol Exp Ther. 1999 Jul;290(1):281-8 2751996 - Biochemistry. 1989 May 2;28(9):3798-803 6306654 - Proc Natl Acad Sci U S A. 1983 Jul;80(13):3958-62 10383923 - Drug Metab Dispos. 1999 Jul;27(7):798-803 1487823 - J Mol Evol. 1992 Nov;35(5):377-84 9143323 - Arch Biochem Biophys. 1997 Apr 15;340(2):208-14 R Baldwin (9206_CR3) 2005; 312 EJ Douzery (9206_CR6) 2003; 57 D Nelson (9206_CR28) 1996; 6 Y Suwa (9206_CR33) 1985; 260 D Lewis (9206_CR19) 1998; 410 P Nef (9206_CR25) 1989; 264 L Du (9206_CR7) 2004; 195 D Nebert (9206_CR23) 1987; 6 M Shultz (9206_CR32) 1999; 290 H Goldstone (9206_CR9) 2006; 62 M Lee (9206_CR18) 1999; 49 Y Mizukami (9206_CR21) 1983; 80 S Rivera (9206_CR31) 2002; 61 SMG Hoffman (9206_CR10) 1995; 41 A Jean (9206_CR14) 1994; 13 SMG Hoffman (9206_CR11) 2007; 616 C O’hUigin (9206_CR30) 1992; 35 N Chen (9206_CR5) 2002; 499 P Fernandez-Salguero (9206_CR8) 1995; 57 T Aoyama (9206_CR1) 1990; 18 D Nebert (9206_CR24) 2002; 360 D Nelson (9206_CR29) 2004; 14 S Kimura (9206_CR16) 1989; 28 D Keeney (9206_CR15) 1998; 273 E Trottier (9206_CR34) 1996; 52 K Misawa (9206_CR20) 2003; 2 9206_CR26 ST Saarikoski (9206_CR40) 2005; 53 Z Hua (9206_CR13) 1997; 340 H Wang (9206_CR35) 2003; 111 RJ Asher (9206_CR2) 2005; 307 D Nelson (9206_CR27) 1993; 12 SMG Hoffman (9206_CR12) 2001; 11 K Nagata (9206_CR22) 1987; 262 N Brookman-Amissah (9206_CR4) 2001; 22 D Lanza (9206_CR17) 1999; 27 D Werck-Reichhart (9206_CR36) 2000; 1 |
References_xml | – volume: 499 start-page: 151 year: 2002 end-page: 161 ident: CR5 article-title: Identification and cross-species comparisons of subfamily genes in mammals publication-title: Mutat Res contributor: fullname: Hoffman – volume: 360 start-page: 1155 year: 2002 end-page: 1162 ident: CR24 article-title: Clinical importance of the cytochromes P450 publication-title: Lancet doi: 10.1016/S0140-6736(02)11203-7 contributor: fullname: Russell – volume: 6 start-page: 1 year: 1996 end-page: 42 ident: CR28 article-title: The P450 superfamily: update on new sequences, gene mapping, accession numbers, and nomenclature publication-title: Pharmacogenetics doi: 10.1097/00008571-199602000-00002 contributor: fullname: Nebert – volume: 616 start-page: 133 year: 2007 end-page: 138 ident: CR11 article-title: Dynamic evolution of the gene cluster in primates publication-title: Mutat Res contributor: fullname: Hu – volume: 111 start-page: 1835 year: 2003 end-page: 1842 ident: CR35 article-title: Organization and evolution of the gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster publication-title: Environ Health Persp contributor: fullname: Hoffman – volume: 57 start-page: 651 year: 1995 end-page: 660 ident: CR8 article-title: A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human genes and identification of variant alleles publication-title: Amer J Human Genet contributor: fullname: Pelkonen – volume: 264 start-page: 6780 year: 1989 end-page: 6785 ident: CR25 article-title: Olfactory-specific cytochrome P450 publication-title: J Biol Chem contributor: fullname: Hanukoglu – volume: 57 start-page: S201 year: 2003 end-page: S213 ident: CR6 article-title: Local molecular clocks in three nuclear genes: divergence times for rodents and other mammals and incompatibility among fossil calibrations publication-title: J Mol Evol doi: 10.1007/s00239-003-0028-x contributor: fullname: Huchon – volume: 22 start-page: 155 year: 2001 end-page: 160 ident: CR4 article-title: Isolation and sequencing of the cDNA of a novel cytochrome P450 from rat oesophagus publication-title: Carcinogenesis doi: 10.1093/carcin/22.1.155 contributor: fullname: Swann – volume: 28 start-page: 3798 year: 1989 end-page: 3803 ident: CR16 article-title: Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence chromosome mapping, and induction by 3-methylcholanthrene publication-title: Biochemistry doi: 10.1021/bi00435a026 contributor: fullname: Gonzalez – volume: 14 start-page: 1 year: 2004 end-page: 18 ident: CR29 article-title: Comparison of cytochrome P450 ( ) genes from the mouse and human genomes, and nomenclature recommendations for genes, pseudogenes, and alternative splice variants publication-title: Pharmacogenetics doi: 10.1097/00008571-200401000-00001 contributor: fullname: Nebert – volume: 53 start-page: 549 year: 2005 end-page: 556 ident: CR40 article-title: Localization of cytochrome P450CYP2S1 expression in human tissues by in situ hybridization and immunohistochemisty publication-title: J Histochem Cytochem doi: 10.1369/jhc.4C6576.2005 contributor: fullname: Husgafvel-Pursiainen – volume: 262 start-page: 2787 year: 1987 end-page: 2793 ident: CR22 article-title: Rat testosterone 7-hydroxylase publication-title: J Biol Chem contributor: fullname: Gonzalez – volume: 195 start-page: 278 year: 2004 end-page: 287 ident: CR7 article-title: Epidermal family cytochrome P450 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2003.09.020 contributor: fullname: Keeney – volume: 2 start-page: 320 year: 2003 end-page: 327 ident: CR20 article-title: Revisiting the Glires concept–phylogenetic analysis of nuclear sequences publication-title: Mol Phylogenet Evol doi: 10.1016/S1055-7903(03)00079-4 contributor: fullname: Janke – volume: 312 start-page: 857 year: 2005 end-page: 865 ident: CR3 article-title: Bioactivation of the pulmonary toxicants naphthalene and 1-nitronaphthalene by rat CYP2F4 publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.104.075440 contributor: fullname: Buckpitt – volume: 27 start-page: 798 year: 1999 end-page: 803 ident: CR17 article-title: Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells publication-title: Drug Metab Disp contributor: fullname: Yost – volume: 35 start-page: 377 year: 1992 end-page: 384 ident: CR30 article-title: The molecular clock ticks regularly in muroid rodents and hamsters publication-title: J Mol Evol doi: 10.1007/BF00171816 contributor: fullname: Li – volume: 13 start-page: 781 year: 1994 end-page: 792 ident: CR14 article-title: Rat liver cytochrome P450 : structure of the gene and immunological identification of a constitutive P450 -like protein in rat liver publication-title: DNA Cell Biol doi: 10.1089/dna.1994.13.781 contributor: fullname: Trottier – volume: 62 start-page: 708 year: 2006 end-page: 717 ident: CR9 article-title: A revised evolutionary history of the subfamily: gene duplication, gene conversion, and positive selection publication-title: J Mol Evol doi: 10.1007/s00239-005-0134-z contributor: fullname: Stegeman – volume: 12 start-page: 1 year: 1993 end-page: 15 ident: CR27 article-title: The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names or enzymes and nomenclature publication-title: DNA Cell Biol contributor: fullname: Nebert – volume: 80 start-page: 3958 year: 1983 end-page: 3962 ident: CR21 article-title: Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver publication-title: P Natl Acad Sci-Biol doi: 10.1073/pnas.80.13.3958 contributor: fullname: Fujii-Kuriyama – volume: 41 start-page: 894 year: 1995 end-page: 900 ident: CR10 article-title: Organization and evolution of the gene subfamily cluster on human chromosome 19 publication-title: J Mol Evol contributor: fullname: Gonzalez – volume: 273 start-page: 9279 year: 1998 end-page: 9284 ident: CR15 article-title: A keratinocyte-specific epoxygenase, , metabolizes arachidonic acid with unusual selectivity, producing a single major eoxyeicosatrienoic acid publication-title: J Biol Chem doi: 10.1074/jbc.273.15.9279 contributor: fullname: Waterman – volume: 290 start-page: 281 year: 1999 end-page: 288 ident: CR32 article-title: Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics publication-title: J Pharmacol Exp Ther contributor: fullname: Buckpitt – volume: 18 start-page: 378 year: 1990 end-page: 382 ident: CR1 article-title: cDNA-directed expression of rat P450s IIA1 and IIA2 publication-title: Drug Metab Disp contributor: fullname: Gelboin – volume: 340 start-page: 208 year: 1997 end-page: 214 ident: CR13 article-title: cDNA cloning, heterologous expression and characterization of mouse , an olfactory-specific steroid hydroxylase publication-title: Arch Biochem Biophys doi: 10.1006/abbi.1997.9899 contributor: fullname: Ding – volume: 52 start-page: 963 year: 1996 end-page: 965 ident: CR34 article-title: Identification of and , two apparent pseudogenes in the rat cytochrome P450 ( ) subfamily publication-title: Biochem Pharmacol doi: 10.1016/0006-2952(96)00411-X contributor: fullname: Anderson – volume: 61 start-page: 255 year: 2002 end-page: 259 ident: CR31 article-title: Identification of a novel dioxin-inducible cytochrome P450 publication-title: Mol Pharmocol doi: 10.1124/mol.61.2.255 contributor: fullname: Hankinson – volume: 307 start-page: 1091 year: 2005 end-page: 1094 ident: CR2 article-title: Stem Lagomorpha and the antiquity of Glires publication-title: Science doi: 10.1126/science.1107808 contributor: fullname: Novacek – volume: 11 start-page: 687 year: 2001 end-page: 698 ident: CR12 article-title: Organization, structure and evolution of the gene cluster on human chromosome 19 publication-title: Pharmacogenetics doi: 10.1097/00008571-200111000-00007 contributor: fullname: Keeney – volume: 49 start-page: 385 year: 1999 end-page: 391 ident: CR18 article-title: Molecular clock calibrations and metazoan divergence dates publication-title: J Mol Evol doi: 10.1007/PL00006562 contributor: fullname: Lee – volume: 1 start-page: 30031 year: 2000 end-page: 30039 ident: CR36 article-title: Cytochrome P450: a success story publication-title: Genome Biol doi: 10.1186/gb-2000-1-6-reviews3003 contributor: fullname: Feyereisen – ident: CR26 – volume: 410 start-page: 245 year: 1998 end-page: 270 ident: CR19 article-title: Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics publication-title: Mutat Res doi: 10.1016/S1383-5742(97)00040-9 contributor: fullname: Lake – volume: 6 start-page: 1 year: 1987 end-page: 11 ident: CR23 article-title: The P450 gene superfamily: recommended nomenclature publication-title: DNA contributor: fullname: Waterman – volume: 260 start-page: 7980 year: 1985 end-page: 7984 ident: CR33 article-title: Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver publication-title: J Biol Chem contributor: fullname: Fujii-Kuriyama – volume: 195 start-page: 278 year: 2004 ident: 9206_CR7 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2003.09.020 contributor: fullname: L Du – volume: 49 start-page: 385 year: 1999 ident: 9206_CR18 publication-title: J Mol Evol doi: 10.1007/PL00006562 contributor: fullname: M Lee – volume: 264 start-page: 6780 year: 1989 ident: 9206_CR25 publication-title: J Biol Chem doi: 10.1016/S0021-9258(18)83497-4 contributor: fullname: P Nef – ident: 9206_CR26 – volume: 111 start-page: 1835 year: 2003 ident: 9206_CR35 publication-title: Environ Health Persp doi: 10.1289/ehp.6546 contributor: fullname: H Wang – volume: 52 start-page: 963 year: 1996 ident: 9206_CR34 publication-title: Biochem Pharmacol doi: 10.1016/0006-2952(96)00411-X contributor: fullname: E Trottier – volume: 53 start-page: 549 year: 2005 ident: 9206_CR40 publication-title: J Histochem Cytochem doi: 10.1369/jhc.4C6576.2005 contributor: fullname: ST Saarikoski – volume: 312 start-page: 857 year: 2005 ident: 9206_CR3 publication-title: J Pharmacol Exp Ther doi: 10.1124/jpet.104.075440 contributor: fullname: R Baldwin – volume: 290 start-page: 281 year: 1999 ident: 9206_CR32 publication-title: J Pharmacol Exp Ther contributor: fullname: M Shultz – volume: 6 start-page: 1 year: 1987 ident: 9206_CR23 publication-title: DNA doi: 10.1089/dna.1987.6.1 contributor: fullname: D Nebert – volume: 13 start-page: 781 year: 1994 ident: 9206_CR14 publication-title: DNA Cell Biol doi: 10.1089/dna.1994.13.781 contributor: fullname: A Jean – volume: 35 start-page: 377 year: 1992 ident: 9206_CR30 publication-title: J Mol Evol contributor: fullname: C O’hUigin – volume: 307 start-page: 1091 year: 2005 ident: 9206_CR2 publication-title: Science doi: 10.1126/science.1107808 contributor: fullname: RJ Asher – volume: 12 start-page: 1 year: 1993 ident: 9206_CR27 publication-title: DNA Cell Biol doi: 10.1089/dna.1993.12.1 contributor: fullname: D Nelson – volume: 360 start-page: 1155 year: 2002 ident: 9206_CR24 publication-title: Lancet doi: 10.1016/S0140-6736(02)11203-7 contributor: fullname: D Nebert – volume: 27 start-page: 798 year: 1999 ident: 9206_CR17 publication-title: Drug Metab Disp contributor: fullname: D Lanza – volume: 14 start-page: 1 year: 2004 ident: 9206_CR29 publication-title: Pharmacogenetics doi: 10.1097/00008571-200401000-00001 contributor: fullname: D Nelson – volume: 616 start-page: 133 year: 2007 ident: 9206_CR11 publication-title: Mutat Res doi: 10.1016/j.mrfmmm.2006.11.004 contributor: fullname: SMG Hoffman – volume: 6 start-page: 1 year: 1996 ident: 9206_CR28 publication-title: Pharmacogenetics doi: 10.1097/00008571-199602000-00002 contributor: fullname: D Nelson – volume: 28 start-page: 3798 year: 1989 ident: 9206_CR16 publication-title: Biochemistry doi: 10.1021/bi00435a026 contributor: fullname: S Kimura – volume: 57 start-page: S201 year: 2003 ident: 9206_CR6 publication-title: J Mol Evol doi: 10.1007/s00239-003-0028-x contributor: fullname: EJ Douzery – volume: 61 start-page: 255 year: 2002 ident: 9206_CR31 publication-title: Mol Pharmocol doi: 10.1124/mol.61.2.255 contributor: fullname: S Rivera – volume: 340 start-page: 208 year: 1997 ident: 9206_CR13 publication-title: Arch Biochem Biophys doi: 10.1006/abbi.1997.9899 contributor: fullname: Z Hua – volume: 80 start-page: 3958 year: 1983 ident: 9206_CR21 publication-title: P Natl Acad Sci-Biol doi: 10.1073/pnas.80.13.3958 contributor: fullname: Y Mizukami – volume: 62 start-page: 708 year: 2006 ident: 9206_CR9 publication-title: J Mol Evol doi: 10.1007/s00239-005-0134-z contributor: fullname: H Goldstone – volume: 262 start-page: 2787 year: 1987 ident: 9206_CR22 publication-title: J Biol Chem doi: 10.1016/S0021-9258(18)61575-3 contributor: fullname: K Nagata – volume: 18 start-page: 378 year: 1990 ident: 9206_CR1 publication-title: Drug Metab Disp contributor: fullname: T Aoyama – volume: 410 start-page: 245 year: 1998 ident: 9206_CR19 publication-title: Mutat Res doi: 10.1016/S1383-5742(97)00040-9 contributor: fullname: D Lewis – volume: 260 start-page: 7980 year: 1985 ident: 9206_CR33 publication-title: J Biol Chem doi: 10.1016/S0021-9258(17)39550-9 contributor: fullname: Y Suwa – volume: 22 start-page: 155 year: 2001 ident: 9206_CR4 publication-title: Carcinogenesis doi: 10.1093/carcin/22.1.155 contributor: fullname: N Brookman-Amissah – volume: 273 start-page: 9279 year: 1998 ident: 9206_CR15 publication-title: J Biol Chem doi: 10.1074/jbc.273.15.9279 contributor: fullname: D Keeney – volume: 499 start-page: 151 year: 2002 ident: 9206_CR5 publication-title: Mutat Res doi: 10.1016/S0027-5107(01)00274-3 contributor: fullname: N Chen – volume: 11 start-page: 687 year: 2001 ident: 9206_CR12 publication-title: Pharmacogenetics doi: 10.1097/00008571-200111000-00007 contributor: fullname: SMG Hoffman – volume: 41 start-page: 894 year: 1995 ident: 9206_CR10 publication-title: J Mol Evol contributor: fullname: SMG Hoffman – volume: 57 start-page: 651 year: 1995 ident: 9206_CR8 publication-title: Amer J Human Genet contributor: fullname: P Fernandez-Salguero – volume: 2 start-page: 320 year: 2003 ident: 9206_CR20 publication-title: Mol Phylogenet Evol doi: 10.1016/S1055-7903(03)00079-4 contributor: fullname: K Misawa – volume: 1 start-page: 30031 year: 2000 ident: 9206_CR36 publication-title: Genome Biol doi: 10.1186/gb-2000-1-6-reviews3003 contributor: fullname: D Werck-Reichhart |
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SubjectTerms | Animal Genetics and Genomics Animals Aryl Hydrocarbon Hydroxylases - genetics Biomedical and Life Sciences Chromosomal rearrangement Chromosome 1 CYP2ABFGST cluster cytochrome P-450 Cytochrome P-450 CYP2B1 - genetics Cytochrome P-450 Enzyme System - genetics Cytochrome P450 Family 2 Evolution, Molecular Evolutionary Biology Gene evolution Gene family Human Genetics Humans Life Sciences Mammals Mice Microbial Genetics and Genomics Multigene Family Phylogeny Plant Genetics and Genomics Primates Primates - genetics Rats Rodentia - genetics Rodents Steroid Hydroxylases - genetics |
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Title | Evolution of the CYP2ABFGST gene cluster in rat, and a fine-scale comparison among rodent and primate species |
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