Clinical Impact of Skin Lesions in Mastocytosis: A Multicenter Study of the European Competence Network on Mastocytosis

• Published in: Journal of Investigative Dermatology Vol. 141; no. 7; pp. 1719 - 1727
• Main Authors: Aberer, Elisabeth, Sperr, Wolfgang R., Bretterklieber, Agnes, Avian, Alexander, Hadzijusufovic, Emir, Kluin-Nelemans, Hanneke C., Oude Elberink, Hanneke, van Anrooij, Björn, Niedoszytko, Marek, Lange, Magdalena, Górska, Aleksandra, Elena, Chiara, Brazzelli, Valeria, Belloni Fortina, Anna, Caroppo, Francesca, Hartmann, Karin, Illerhaus, Anja, Reiter, Andreas, Jawhar, Mohamad, Bonadonna, Patrizia, Zanotti, Roberta, Triggiani, Massimo, Parente, Roberta, Gotlib, Jason, Doubek, Michael, von Bubnoff, Nikolas, Fuchs, David, Sabato, Vito, Brockow, Knut, Jäkel, Nadja, Panse, Jens, Valent, Peter
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2021; Elsevier BV
• Subjects: Adolescent; Adult; ADULTS; Aged; Biopsy; Bone Marrow; Bone Marrow - pathology; Child; Child, Preschool; CLASSIFICATION; ddc:no; DIAGNOSIS; Diagnosis, Differential; DISEASE; Female; Human medicine; Humans; Infant; Male; Mast Cells - pathology; MAST-CELLS; Mastocytosis, Cutaneous; Mastocytosis, Cutaneous - diagnosis; Mastocytosis, Cutaneous - epidemiology; Mastocytosis, Cutaneous - pathology; Mastocytosis, Systemic; Mastocytosis, Systemic - diagnosis; Mastocytosis, Systemic - mortality; Mastocytosis, Systemic - pathology; Mastocytosis; categories; cutaneous; progression; skin involvement; subtypes; systemic; tryptase; Middle Aged; PEDIATRIC MASTOCYTOSIS; Prognosis; Registries; Registries - statistics & numerical data; RISK; Skin; Skin - pathology; Survival Analysis; SYSTEMIC MASTOCYTOSIS; Time Factors; URTICARIA PIGMENTOSA; Young Adult; SM-AHN; ISM; BMM; OS; MPCM; CM; BM; IQR; SSM; DCM; BSA; PUVA; MC; MCM; MIS; MCL; SM; ASM; ECNM; WHO

Mastocytosis is a rare neoplasm characterized by the expansion and accumulation of mast cells in various organ systems. Systemic mastocytosis (SM) may or may not present with cutaneous lesions. To examine the frequency and clinical impact of cutaneous involvement, data on 1,510 patients with mastocy...