Chemometric tools improving the determination of anti-inflammatory and antiepileptic drugs in river and wastewater by solid-phase microextraction and liquid chromatography diode array detection

• Published in: Journal of Chromatography A Vol. 1216; no. 29; pp. 5489 - 5496
• Main Authors: García, M.D. Gil, Cañada, F. Cañada, Culzoni, M.J., Vera-Candioti, L., Siano, G.G., Goicoechea, H.C., Galera, M. Martínez
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 17.07.2009; Amsterdam; New York: Elsevier; Elsevier
• Subjects: Analysis methods; Analytical chemistry; Anti-Inflammatory Agents, Non-Steroidal - analysis; Anticonvulsants - analysis; Applied sciences; Chemistry; Chromatographic methods and physical methods associated with chromatography; Chromatography, Liquid - methods; Exact sciences and technology; Freshwater; Liquid chromatography–diode array detection; Natural water pollution; Other chromatographic methods; Other wastewaters; Pharmaceuticals; Pollution; River water; Second order advantage; Sewage - analysis; Solid Phase Microextraction - methods; Solid-phase microextraction; Wastewater; Wastewaters; Water Pollutants, Chemical - analysis; Water treatment and pollution; Solid-phase microextraction; Liquid chromatography–diode array detection; Second order advantage; Wastewater; River water; Pharmaceuticals; Trace analysis; Chemical analysis; Antiinflammatory agent; Anticonvulsant; Liquid chromatography; Waste water; Chemical enrichment; Solid phase microextraction; Ultraviolet detector; Sample preparation; Surface water; Diode array; Water pollution; Liquid chromatography-diode array detection; Chemometrics; Quantitative analysis

An analytical method for the simultaneous determination of seven non-steroidal anti-inflammatory drugs (naproxen, ketoprofen, diclofenac, piroxicam, indomethacin, sulindac and diflunisal) and the anticonvulsant carbamazepine in river and wastewater is reported. The method involves pre-concentration...