Prophylactic platelet transfusions in patients with blood malignancies: cost analysis of a randomized trial

• Published in: Transfusion (Philadelphia, Pa.) Vol. 54; no. 10; pp. 2394 - 2403
• Main Authors: Campbell, Helen E., Estcourt, Lise J., Stokes, Elizabeth A., Llewelyn, Charlotte A., Murphy, Michael F., Wood, Erica M., Stanworth, Simon J.
• Format: Journal Article
• Language: English
• Published: Hoboken, NJ Blackwell Publishing Ltd 01.10.2014; Wiley; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Cost-Benefit Analysis; Erythrocyte Transfusion - economics; Female; Health Care Costs; Hematologic Neoplasms - economics; Hematologic Neoplasms - therapy; Hematopoietic Stem Cell Transplantation - adverse effects; Hemorrhage - economics; Hemorrhage - prevention & control; Humans; Male; Medical sciences; Middle Aged; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Platelet Transfusion - economics; Primary Prevention - economics; Primary Prevention - methods; Quality of Life; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Transplantation, Homologous; Tumors; Human; Prevention; Randomization; Platelet; Transfusion; Health economy; Clinical trial; Patient; Malignant tumor; Cost analysis; Blood; Cancer

Background This cost analysis uses data from a randomized trial comparing a no prophylaxis versus prophylactic platelet (PLT) transfusion policy (counts <10 × 109/L) in adult patients with hematologic malignancies. Results are presented for all patients and separately for autologous hematopoietic...