Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers

• Published in: Clinical and Translational Medicine Vol. 5; no. 1; pp. 1 - 16
• Main Authors: Brücher, Björn L. D. M., Li, Yan, Schnabel, Philipp, Daumer, Martin, Wallace, Timothy J., Kube, Rainer, Zilberstein, Bruno, Steele, Scott, Voskuil, Jan L. A., Jamall, Ijaz S.
• Format: Journal Article Book Review
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 06.04.2016; John Wiley & Sons, Inc
• Subjects: Barrett carcinoma; Clinical Genomics; Epigenetics; Esophageal adenocarcinoma; Esophageal carcinoma; Esophageal squamous cell carcinoma; Genomics; Medicine; Medicine & Public Health; MicroRNA; Multimodal therapy; Neoadjuvant therapy; Prognosis; Proteomics; Response; Review; Survival; Upper gastrointestinal tract; Esophageal carcinoma; Neoadjuvant therapy; Multimodal therapy; Prognosis; Genomics; Upper gastrointestinal tract; Survival; Response; MicroRNA; Barrett carcinoma; Proteomics; Epigenetics; Esophageal squamous cell carcinoma; Esophageal adenocarcinoma

One major objective for our evolving understanding in the treatment of cancers will be to address how a combination of diagnosis and treatment strategies can be used to integrate patient and tumor variables with an outcome-oriented approach. Such an approach, in a multimodal therapy setting, could i...