Lack of association of LOXL1 gene variants in Japanese patients with central retinal vein occlusion without clinically detectable pseudoexfoliation material deposits

• Published in: Acta ophthalmologica (Oxford, England) Vol. 93; no. 3; pp. e214 - e217
• Main Authors: Tanito, Masaki, Hara, Katsunori, Akahori, Masakazu, Harata, Ayano, Itabashi, Takeshi, Takai, Yasuyuki, Kaidzu, Sachiko, Ohira, Akihiro, Iwata, Takeshi
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.05.2015
• Subjects: Adult; Aged; Aged, 80 and over; Amino Acid Oxidoreductases - genetics; Asian Continental Ancestry Group - genetics; cataract; Cataract - genetics; central retinal vein occlusion; exfoliation syndrome; Exfoliation Syndrome - genetics; Female; Gene Frequency; Genetic Markers; Genotyping Techniques; Humans; Japan - epidemiology; LOXL1; Male; Middle Aged; Ophthalmology; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Retinal Vein Occlusion - genetics; SNPs; Japan; SNPs; exfoliation syndrome; cataract; central retinal vein occlusion; LOXL1

Purpose A possible association has been reported between exfoliation syndrome (EX) and various ocular and systemic vascular disorders; however, it is unclear if there is an association between EX and central retinal vein occlusion (CRVO). Because latent deposits of exfoliation materials might not be...