Pathologic Lower Extremity Fractures in Children With Alagille Syndrome

• Published in: Journal of pediatric gastroenterology and nutrition Vol. 51; no. 1; pp. 66 - 70
• Main Authors: Bales, Christina B, Kamath, Binita M, Munoz, Pedro S, Nguyen, Alexander, Piccoli, David A, Spinner, Nancy B, Horn, David, Shults, Justine, Leonard, Mary B, Grimberg, Adda, Loomes, Kathleen M
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.07.2010
• Subjects: Adolescent; Adult; Age Factors; Alagille syndrome; Alagille Syndrome - complications; Alagille Syndrome - genetics; Biological and medical sciences; Child; Child, Preschool; Feeding. Feeding behavior; Female; fracture; Fractures, Spontaneous - etiology; Fractures, Spontaneous - genetics; Fundamental and applied biological sciences. Psychology; Gastroenterology. Liver. Pancreas. Abdomen; Health Surveys; Humans; Incidence; Infant; Injuries of the limb. Injuries of the spine; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Lower Extremity - injuries; Male; Medical sciences; osteomalacia; Other diseases. Semiology; Retrospective Studies; Risk Factors; Traumas. Diseases due to physical agents; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Young Adult; Human; Pathologic fracture; Portal circulation disease; Alagille syndrome; Diseases of the osteoarticular system; Nutrition disorder; Vitamin deficiency; Cardiovascular disease; Arteriohepatic dysplasia; Metabolic diseases; Lower extremity; fracture; Vascular disease; Metabolic disorder; Vitamin D; Gastroenterology; Digestive diseases; Bone; Osteomalacia; Child; Nutritional status

ABSTRACT Objectives: In this retrospective study, we aimed to determine the incidence and distribution of fractures in patients with Alagille syndrome, 1 of the leading inherited causes of pediatric cholestatic liver disease. Materials and Methods: Surveys regarding growth, nutrition, and organ invo...