Effects of transcranial photobiomodulation with near‐infrared light on sexual dysfunction

Objectives Transcranial photobiomodulation (t‐PBM) consists of the delivery of near‐infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t‐PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of...

Full description

Saved in:
Bibliographic Details
Published inLasers in surgery and medicine Vol. 51; no. 2; pp. 127 - 135
Main Authors Cassano, Paolo, Dording, Christina, Thomas, Garrett, Foster, Simmie, Yeung, Albert, Uchida, Mai, Hamblin, Michael R., Bui, Eric, Fava, Maurizio, Mischoulon, David, Iosifescu, Dan V.
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 01.02.2019
Subjects
Adolescent
Adult
Aged
Antidepressants
Arousal
Brain
Brain - radiation effects
Cerebral cortex
Depressive Disorder, Major - therapy
Double-Blind Method
Humans
Infrared radiation
Infrared Rays - therapeutic use
Lasers
Light therapy
Low-Level Light Therapy - methods
Mental depression
Middle Aged
photobiomodulation
Scalp
Sexual behavior
sexual dysfunction
Sexual Dysfunctions, Psychological - therapy
Therapy
transcranial
photobiomodulation
transcranial
sexual dysfunction
Online AccessGet full text

Cover

Abstract Objectives Transcranial photobiomodulation (t‐PBM) consists of the delivery of near‐infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t‐PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t‐PBM on sexual dysfunction. Methods We performed a secondary analysis of a double‐blind clinical trial on t‐PBM for major depressive disorder (MDD). Twenty individuals received NIR t‐PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment‐Emergent Effects‐Specific Inquiry (SAFTEE‐SI). Results The mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t‐PBM in NIR‐mode was significantly greater than in subjects receiving sham‐mode in the whole sample (NIR [n = 9] −2.55 ± 1.88 vs. sham [n = 11] −0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] −3.4 ± 1.95 vs. sham [n = 7] −0.14 ± 1.21; z = 2.576, P = 0.010]). Conclusion This exploratory study with a small sample size indicates that repeated sessions of NIR t‐PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t‐PBM in our cohort. Lasers Surg. Med. 51:127–135, 2019. © 2018 Wiley Periodicals, Inc.
AbstractList Transcranial photobiomodulation (t-PBM) consists of the delivery of near-infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t-PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t-PBM on sexual dysfunction. We performed a secondary analysis of a double-blind clinical trial on t-PBM for major depressive disorder (MDD). Twenty individuals received NIR t-PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment-Emergent Effects-Specific Inquiry (SAFTEE-SI). The mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t-PBM in NIR-mode was significantly greater than in subjects receiving sham-mode in the whole sample (NIR [n = 9] -2.55 ± 1.88 vs. sham [n = 11] -0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] -3.4 ± 1.95 vs. sham [n = 7] -0.14 ± 1.21; z = 2.576, P = 0.010]). This exploratory study with a small sample size indicates that repeated sessions of NIR t-PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t-PBM in our cohort. Lasers Surg. Med. 51:127-135, 2019. © 2018 Wiley Periodicals, Inc.
Transcranial photobiomodulation (t-PBM) consists of the delivery of near-infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t-PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t-PBM on sexual dysfunction.OBJECTIVESTranscranial photobiomodulation (t-PBM) consists of the delivery of near-infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t-PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t-PBM on sexual dysfunction.We performed a secondary analysis of a double-blind clinical trial on t-PBM for major depressive disorder (MDD). Twenty individuals received NIR t-PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment-Emergent Effects-Specific Inquiry (SAFTEE-SI).METHODSWe performed a secondary analysis of a double-blind clinical trial on t-PBM for major depressive disorder (MDD). Twenty individuals received NIR t-PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment-Emergent Effects-Specific Inquiry (SAFTEE-SI).The mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t-PBM in NIR-mode was significantly greater than in subjects receiving sham-mode in the whole sample (NIR [n = 9] -2.55 ± 1.88 vs. sham [n = 11] -0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] -3.4 ± 1.95 vs. sham [n = 7] -0.14 ± 1.21; z = 2.576, P = 0.010]).RESULTSThe mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t-PBM in NIR-mode was significantly greater than in subjects receiving sham-mode in the whole sample (NIR [n = 9] -2.55 ± 1.88 vs. sham [n = 11] -0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] -3.4 ± 1.95 vs. sham [n = 7] -0.14 ± 1.21; z = 2.576, P = 0.010]).This exploratory study with a small sample size indicates that repeated sessions of NIR t-PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t-PBM in our cohort. Lasers Surg. Med. 51:127-135, 2019. © 2018 Wiley Periodicals, Inc.CONCLUSIONThis exploratory study with a small sample size indicates that repeated sessions of NIR t-PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t-PBM in our cohort. Lasers Surg. Med. 51:127-135, 2019. © 2018 Wiley Periodicals, Inc.
Objectives Transcranial photobiomodulation (t‐PBM) consists of the delivery of near‐infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t‐PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t‐PBM on sexual dysfunction. Methods We performed a secondary analysis of a double‐blind clinical trial on t‐PBM for major depressive disorder (MDD). Twenty individuals received NIR t‐PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment‐Emergent Effects‐Specific Inquiry (SAFTEE‐SI). Results The mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t‐PBM in NIR‐mode was significantly greater than in subjects receiving sham‐mode in the whole sample (NIR [n = 9] −2.55 ± 1.88 vs. sham [n = 11] −0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] −3.4 ± 1.95 vs. sham [n = 7] −0.14 ± 1.21; z = 2.576, P = 0.010]). Conclusion This exploratory study with a small sample size indicates that repeated sessions of NIR t‐PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t‐PBM in our cohort. Lasers Surg. Med. 51:127–135, 2019. © 2018 Wiley Periodicals, Inc.
ObjectivesTranscranial photobiomodulation (t‐PBM) consists of the delivery of near‐infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t‐PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t‐PBM on sexual dysfunction.MethodsWe performed a secondary analysis of a double‐blind clinical trial on t‐PBM for major depressive disorder (MDD). Twenty individuals received NIR t‐PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment‐Emergent Effects‐Specific Inquiry (SAFTEE‐SI).ResultsThe mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t‐PBM in NIR‐mode was significantly greater than in subjects receiving sham‐mode in the whole sample (NIR [n = 9] −2.55 ± 1.88 vs. sham [n = 11] −0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] −3.4 ± 1.95 vs. sham [n = 7] −0.14 ± 1.21; z = 2.576, P = 0.010]).ConclusionThis exploratory study with a small sample size indicates that repeated sessions of NIR t‐PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t‐PBM in our cohort. Lasers Surg. Med. 51:127–135, 2019. © 2018 Wiley Periodicals, Inc.
Author Yeung, Albert
Hamblin, Michael R.
Cassano, Paolo
Foster, Simmie
Bui, Eric
Thomas, Garrett
Fava, Maurizio
Uchida, Mai
Dording, Christina
Mischoulon, David
Iosifescu, Dan V.
AuthorAffiliation 3 Department of Psychiatry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York
1 Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts
2 Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts
AuthorAffiliation_xml – name: 2 Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts
– name: 1 Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts
– name: 3 Department of Psychiatry, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York
Author_xml – sequence: 1
  givenname: Paolo
  surname: Cassano
  fullname: Cassano, Paolo
  organization: Massachusetts General Hospital
– sequence: 2
  givenname: Christina
  surname: Dording
  fullname: Dording, Christina
  organization: Massachusetts General Hospital
– sequence: 3
  givenname: Garrett
  surname: Thomas
  fullname: Thomas, Garrett
  organization: Massachusetts General Hospital
– sequence: 4
  givenname: Simmie
  surname: Foster
  fullname: Foster, Simmie
  organization: Massachusetts General Hospital
– sequence: 5
  givenname: Albert
  surname: Yeung
  fullname: Yeung, Albert
  organization: Massachusetts General Hospital
– sequence: 6
  givenname: Mai
  surname: Uchida
  fullname: Uchida, Mai
  organization: Massachusetts General Hospital
– sequence: 7
  givenname: Michael R.
  surname: Hamblin
  fullname: Hamblin, Michael R.
  organization: Massachusetts General Hospital
– sequence: 8
  givenname: Eric
  surname: Bui
  fullname: Bui, Eric
  organization: Massachusetts General Hospital
– sequence: 9
  givenname: Maurizio
  surname: Fava
  fullname: Fava, Maurizio
  organization: Massachusetts General Hospital
– sequence: 10
  givenname: David
  surname: Mischoulon
  fullname: Mischoulon, David
  organization: Massachusetts General Hospital
– sequence: 11
  givenname: Dan V.
  surname: Iosifescu
  fullname: Iosifescu, Dan V.
  organization: Nathan Kline Institute for Psychiatric Research
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30221776$$D View this record in MEDLINE/PubMed
BookMark eNp1kU1uFDEQhS0URCaBBRdALbGBxSRVtvvHGyQUhR9pEAtgxcJy2-6MI7c92N2E2XEEzshJcDITBBFsXJbqe0-vqo7IQYjBEvIY4QQB6KnP4wllgHiPLBBEsxQIeEAWgOXfgaCH5CjnSwBgFNoH5JABpdi2zYJ8Ph8Gq6dcxaGakgpZl8cpX23WcYq9i2M0s1eTi6G6ctO6Claln99_uDAklaypvLtYT1XpZvttLjqzzcMc9LXgIbk_KJ_to309Jp9enX88e7NcvX_99uzlaqm5QFyKztScNtgqamvOGDKmOFWD6Num6YCKrmcG-9a0neBal67uemgpclMbLgZ2TF7sfDdzP1qjbSiTeLlJblRpK6Ny8u9OcGt5Eb_KhnW0rpti8GxvkOKX2eZJji5r670KNs5ZUoSO8ppxWtCnd9DLOKdQxpOUMSYYAheFevJnot9RbvdegNMdoFPMOdlBajfdbLkEdF4iyOvLynJZeXPZonh-R3Fr-i92737lvN3-H5SrD-92il8FqrP-
CitedBy_id crossref_primary_10_1007_s40501_024_00321_0
crossref_primary_10_3390_neurosci6010026
crossref_primary_10_1089_photob_2019_4678
crossref_primary_10_1089_photob_2020_4986
crossref_primary_10_1097_HRP_0000000000000363
crossref_primary_10_3390_photonics9080507
crossref_primary_10_1002_lsm_23082
crossref_primary_10_3390_photonics9050330
crossref_primary_10_1186_s12984_024_01351_8
crossref_primary_10_1186_s12906_022_03562_9
crossref_primary_10_3389_fpsyt_2021_713686
crossref_primary_10_1002_lsm_23232
crossref_primary_10_1249_JSR_0000000000000752
crossref_primary_10_3389_fpsyt_2020_00827
crossref_primary_10_3389_fpsyt_2023_1267415
Cites_doi 10.1016/j.maturitas.2011.06.011
10.1089/pho.2018.4490
10.1016/j.nlm.2016.12.016
10.1159/000126625
10.1097/00004850-199807006-00001
10.1016/S0022-3999(02)00304-5
10.1007/s11920-018-0883-1
10.1155/2014/841798
10.1038/nrendo.2017.69
10.1016/S0165-0327(99)00050-6
10.1016/j.bbacli.2016.09.002
10.1016/j.neuroscience.2012.11.016
10.1117/1.NPh.3.3.031404
10.1186/1744-9081-5-46
10.1001/jama.281.6.537
10.1007/s10103-016-1962-3
10.1016/j.bbrc.2017.03.131
10.1016/j.jad.2017.06.009
10.1111/jnp.12074
10.1016/j.psc.2016.04.006
10.1155/2015/352979
10.1097/00004714-199212000-00017
10.1007/s10103-017-2221-y
ContentType Journal Article
Copyright 2018 Wiley Periodicals, Inc.
2019 Wiley Periodicals, Inc.
Copyright_xml – notice: 2018 Wiley Periodicals, Inc.
– notice: 2019 Wiley Periodicals, Inc.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
8FD
FR3
K9.
M7Z
P64
7X8
5PM
DOI 10.1002/lsm.23011
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Technology Research Database
Engineering Research Database
ProQuest Health & Medical Complete (Alumni)
Biochemistry Abstracts 1
Biotechnology and BioEngineering Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Biochemistry Abstracts 1
ProQuest Health & Medical Complete (Alumni)
Engineering Research Database
Technology Research Database
Biotechnology and BioEngineering Abstracts
MEDLINE - Academic
DatabaseTitleList MEDLINE
MEDLINE - Academic

Biochemistry Abstracts 1
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Engineering
Physics
EISSN 1096-9101
EndPage 135
ExternalDocumentID PMC6382556
30221776
10_1002_lsm_23011
LSM23011
Genre article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Journal Article
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: Harvard Catalyst Program
– fundername: Harvard Catalyst, The Harvard Clinical and Translational Science Center (National Center for Advancing Translational Sciences, National Institutes of Health Award)
  funderid: UL1 TR001102
– fundername: Brain and Behavior Research Foundation
– fundername: NIAID NIH HHS
  grantid: R01 AI050875
– fundername: NCATS NIH HHS
  grantid: UL1 TR001102
– fundername: NIAID NIH HHS
  grantid: R21 AI121700
GroupedDBID ---
.3N
.GA
.GJ
.Y3
05W
0R~
10A
1L6
1OB
1OC
1ZS
31~
33P
3SF
3WU
4.4
4ZD
50Y
50Z
51W
51X
52M
52N
52O
52P
52R
52S
52T
52U
52V
52W
52X
53G
5GY
5RE
5VS
66C
702
7PT
8-0
8-1
8-3
8-4
8-5
8UM
930
A01
A03
AAESR
AAEVG
AAHHS
AAHQN
AAIPD
AAMNL
AANHP
AANLZ
AAONW
AAQQT
AASGY
AAWTL
AAXRX
AAYCA
AAZKR
ABCQN
ABCUV
ABEML
ABIJN
ABJNI
ABPVW
ABQWH
ABXGK
ACAHQ
ACBWZ
ACCFJ
ACCZN
ACGFS
ACGOF
ACIWK
ACMXC
ACPOU
ACPRK
ACRPL
ACSCC
ACXBN
ACXQS
ACYXJ
ADBBV
ADBTR
ADEOM
ADIZJ
ADKYN
ADMGS
ADNMO
ADOZA
ADXAS
ADZMN
AEEZP
AEIGN
AEIMD
AENEX
AEQDE
AEUQT
AEUYR
AFBPY
AFFNX
AFFPM
AFGKR
AFPWT
AFRAH
AFWVQ
AFZJQ
AHBTC
AHMBA
AIACR
AITYG
AIURR
AIWBW
AJBDE
ALAGY
ALMA_UNASSIGNED_HOLDINGS
ALUQN
ALVPJ
AMBMR
AMYDB
ASPBG
ATUGU
AVWKF
AZBYB
AZFZN
AZVAB
BAFTC
BDRZF
BFHJK
BHBCM
BMXJE
BROTX
BRXPI
BY8
C45
CS3
D-6
D-7
D-E
D-F
DCZOG
DPXWK
DR2
DRFUL
DRMAN
DRSTM
DU5
EBD
EBS
EJD
EMOBN
F00
F01
F04
F5P
FEDTE
FUBAC
G-S
G.N
GNP
GODZA
H.X
HBH
HF~
HGLYW
HHY
HHZ
HJTMK
HVGLF
HZ~
IX1
J0M
JPC
KBYEO
KQQ
LATKE
LAW
LC2
LC3
LEEKS
LH4
LITHE
LOXES
LP6
LP7
LUTES
LW6
LYRES
M65
MEWTI
MK4
MRFUL
MRMAN
MRSTM
MSFUL
MSMAN
MSSTM
MXFUL
MXMAN
MXSTM
N04
N05
N9A
NF~
NNB
O66
O9-
OIG
OVD
P2P
P2W
P2X
P2Z
P4B
P4D
PALCI
PQQKQ
Q.N
Q11
QB0
QRW
R.K
RGB
RIWAO
RJQFR
ROL
RWI
RX1
RYL
SAMSI
SUPJJ
SV3
TEORI
UB1
V2E
W8V
W99
WBKPD
WHWMO
WIB
WIH
WIJ
WIK
WJL
WOHZO
WQJ
WRC
WUP
WVDHM
WXI
WXSBR
XG1
XPP
XV2
ZGI
ZZTAW
~IA
~WT
AAYXX
AGHNM
AGQPQ
AGYGG
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
8FD
AAMMB
AEFGJ
AGXDD
AIDQK
AIDYY
FR3
K9.
M7Z
P64
7X8
5PM
ID FETCH-LOGICAL-c4911-98d542617a2e5433133a42af9b76680298b3d1b7d7894cc33ac8b07214d5d49f3
IEDL.DBID DR2
ISSN 0196-8092
1096-9101
IngestDate Thu Aug 21 14:06:08 EDT 2025
Fri Jul 11 09:28:53 EDT 2025
Sun Jul 20 13:41:18 EDT 2025
Thu Apr 03 07:08:56 EDT 2025
Thu Apr 24 23:04:58 EDT 2025
Tue Jul 01 02:22:30 EDT 2025
Wed Jan 22 16:20:58 EST 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords photobiomodulation
transcranial
sexual dysfunction
Language English
License 2018 Wiley Periodicals, Inc.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c4911-98d542617a2e5433133a42af9b76680298b3d1b7d7894cc33ac8b07214d5d49f3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ObjectType-Undefined-3
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/6382556
PMID 30221776
PQID 2333931049
PQPubID 1016352
PageCount 9
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_6382556
proquest_miscellaneous_2108245342
proquest_journals_2333931049
pubmed_primary_30221776
crossref_citationtrail_10_1002_lsm_23011
crossref_primary_10_1002_lsm_23011
wiley_primary_10_1002_lsm_23011_LSM23011
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate February 2019
PublicationDateYYYYMMDD 2019-02-01
PublicationDate_xml – month: 02
  year: 2019
  text: February 2019
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: Hoboken
PublicationTitle Lasers in surgery and medicine
PublicationTitleAlternate Lasers Surg Med
PublicationYear 2019
Publisher Wiley Subscription Services, Inc
Publisher_xml – name: Wiley Subscription Services, Inc
References 2016; 6
2016; 3
2002; 53
1999; 281
2008; 29
2017; 11
2011; 70
2017; 32
2017; 13
2015; 2015
1999; 56
2016; 31
2018
2014; 2014
2009; 5
2013; 230
2017; 221
2016; 39
2017; 486
2018; 20
1992; 12
2017; 139
1998; 13
e_1_2_8_17_1
e_1_2_8_18_1
e_1_2_8_19_1
e_1_2_8_13_1
e_1_2_8_24_1
e_1_2_8_14_1
e_1_2_8_15_1
e_1_2_8_16_1
e_1_2_8_3_1
e_1_2_8_2_1
e_1_2_8_5_1
e_1_2_8_4_1
e_1_2_8_7_1
e_1_2_8_6_1
e_1_2_8_9_1
e_1_2_8_8_1
e_1_2_8_20_1
e_1_2_8_10_1
e_1_2_8_21_1
e_1_2_8_11_1
e_1_2_8_22_1
e_1_2_8_12_1
e_1_2_8_23_1
References_xml – volume: 56
  start-page: 201
  issue: 2‐3
  year: 1999
  end-page: 208
  article-title: Sexual dysfunction before antidepressant therapy in major depression
  publication-title: J Affect Disord
– volume: 2014
  start-page: 841798
  year: 2014
  article-title: Sexual enhancement products for sale online: Raising awareness of the psychoactive effects of yohimbine, maca, horny goat weed, and Ginkgo biloba
  publication-title: Biomed Res Int
– volume: 281
  start-page: 537
  issue: 6
  year: 1999
  end-page: 544
  article-title: Sexual dysfunction in the United States: Prevalence and predictors
  publication-title: JAMA
– volume: 139
  start-page: 69
  year: 2017
  end-page: 75
  article-title: Transcranial infrared laser stimulation improves rule‐based, but not information‐integration, category learning in humans
  publication-title: Neurobiol Learn Mem
– volume: 486
  start-page: 945
  issue: 4
  year: 2017
  end-page: 950
  article-title: Pretreatment with light‐emitting diode therapy reduces ischemic brain injury in mice through endothelial nitric oxide synthase‐dependent mechanisms
  publication-title: Biochem Biophys Res Commun
– volume: 70
  start-page: 37
  issue: 1
  year: 2011
  end-page: 41
  article-title: Complementary and alternative medicine (CAM) for sexual dysfunction and erectile dysfunction in older men and women: An overview of systematic reviews
  publication-title: Maturitas
– volume: 31
  start-page: 1151
  issue: 6
  year: 2016
  end-page: 1160
  article-title: Cognitive enhancement by transcranial laser stimulation and acute aerobic exercise
  publication-title: Lasers Med Sci
– volume: 11
  start-page: 14
  issue: 1
  year: 2017
  end-page: 25
  article-title: Improving executive function using transcranial infrared laser stimulation
  publication-title: J Neuropsychol
– volume: 32
  start-page: 1153
  issue: 5
  year: 2017
  end-page: 1162
  article-title: Beneficial neurocognitive effects of transcranial laser in older adults
  publication-title: Lasers Med Sci
– volume: 6
  start-page: 113
  year: 2016
  end-page: 124
  article-title: Shining light on the head: Photobiomodulation for brain disorders
  publication-title: BBA Clin
– volume: 20
  start-page: 18
  issue: 3
  year: 2018
  article-title: Sex differences in the treatment of sexual dysfunction
  publication-title: Curr Psychiatry Rep
– volume: 221
  start-page: 36
  year: 2017
  end-page: 46
  article-title: Multimorbidity and depression: A systematic review and meta‐analysis
  publication-title: J Affect Disord
– volume: 13
  start-page: S1
  issue: Suppl 6
  year: 1998
  end-page: S4
  article-title: Sexual problems in healthy and depressed persons
  publication-title: Int Clin Psychopharmacol
– volume: 230
  start-page: 13
  year: 2013
  end-page: 23
  article-title: Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans
  publication-title: Neuroscience
– volume: 29
  start-page: 70
  year: 2008
  end-page: 88
  article-title: The impact of physical illness on sexual dysfunction
  publication-title: Adv Psychosom Med
– volume: 3
  start-page: 031404
  issue: 3
  year: 2016
  article-title: Review of transcranial photobiomodulation for major depressive disorder: Targeting brain metabolism, inflammation, oxidative stress, and neurogenesis
  publication-title: Neurophotonics
– volume: 39
  start-page: 427
  issue: 3
  year: 2016
  end-page: 463
  article-title: Sexual dysfunction due to psychotropic medications
  publication-title: Psychiatr Clin North Am
– volume: 13
  start-page: 521
  issue: 9
  year: 2017
  end-page: 535
  article-title: The gentle art of saying NO: How nitric oxide gets things done in the hypothalamus
  publication-title: Nat Rev Endocrinol
– volume: 2015
  start-page: 352979
  year: 2015
  article-title: Near‐infrared transcranial radiation for major depressive disorder: Proof of concept study
  publication-title: Psychiatry J
– year: 2018
  article-title: Transcranial photobiomodulation for the treatment of major depressive disorder. The ELATED‐2 pilot trial
  publication-title: Photomed Laser Surg
– volume: 12
  start-page: 448
  issue: 6
  year: 1992
  article-title: General versus specific inquiry with SAFTEE
  publication-title: J Clin Psychopharmacol
– volume: 53
  start-page: 849
  issue: 4
  year: 2002
  end-page: 857
  article-title: Depression and public health—An overview
  publication-title: J Psychosom Res
– volume: 5
  start-page: 46
  year: 2009
  article-title: Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: A pilot study of 10 patients with major depression and anxiety
  publication-title: Behav Brain Funct
– ident: e_1_2_8_10_1
  doi: 10.1016/j.maturitas.2011.06.011
– ident: e_1_2_8_20_1
  doi: 10.1089/pho.2018.4490
– ident: e_1_2_8_16_1
  doi: 10.1016/j.nlm.2016.12.016
– ident: e_1_2_8_3_1
  doi: 10.1159/000126625
– ident: e_1_2_8_4_1
  doi: 10.1097/00004850-199807006-00001
– ident: e_1_2_8_6_1
  doi: 10.1016/S0022-3999(02)00304-5
– ident: e_1_2_8_9_1
  doi: 10.1007/s11920-018-0883-1
– ident: e_1_2_8_11_1
  doi: 10.1155/2014/841798
– ident: e_1_2_8_24_1
  doi: 10.1038/nrendo.2017.69
– ident: e_1_2_8_5_1
  doi: 10.1016/S0165-0327(99)00050-6
– ident: e_1_2_8_12_1
  doi: 10.1016/j.bbacli.2016.09.002
– ident: e_1_2_8_13_1
  doi: 10.1016/j.neuroscience.2012.11.016
– ident: e_1_2_8_19_1
  doi: 10.1117/1.NPh.3.3.031404
– ident: e_1_2_8_18_1
  doi: 10.1186/1744-9081-5-46
– ident: e_1_2_8_2_1
  doi: 10.1001/jama.281.6.537
– ident: e_1_2_8_14_1
  doi: 10.1007/s10103-016-1962-3
– ident: e_1_2_8_23_1
  doi: 10.1016/j.bbrc.2017.03.131
– ident: e_1_2_8_7_1
  doi: 10.1016/j.jad.2017.06.009
– ident: e_1_2_8_15_1
  doi: 10.1111/jnp.12074
– ident: e_1_2_8_8_1
  doi: 10.1016/j.psc.2016.04.006
– ident: e_1_2_8_17_1
  doi: 10.1155/2015/352979
– ident: e_1_2_8_21_1
  doi: 10.1097/00004714-199212000-00017
– ident: e_1_2_8_22_1
  doi: 10.1007/s10103-017-2221-y
SSID ssj0003207
Score 2.3554919
Snippet Objectives Transcranial photobiomodulation (t‐PBM) consists of the delivery of near‐infrared (NIR) or red light to the scalp designed to penetrate to subjacent...
Transcranial photobiomodulation (t-PBM) consists of the delivery of near-infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical...
ObjectivesTranscranial photobiomodulation (t‐PBM) consists of the delivery of near‐infrared (NIR) or red light to the scalp designed to penetrate to subjacent...
SourceID pubmedcentral
proquest
pubmed
crossref
wiley
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 127
SubjectTerms Adolescent
Adult
Aged
Antidepressants
Arousal
Brain
Brain - radiation effects
Cerebral cortex
Depressive Disorder, Major - therapy
Double-Blind Method
Humans
Infrared radiation
Infrared Rays - therapeutic use
Lasers
Light therapy
Low-Level Light Therapy - methods
Mental depression
Middle Aged
photobiomodulation
Scalp
Sexual behavior
sexual dysfunction
Sexual Dysfunctions, Psychological - therapy
Therapy
transcranial
Title Effects of transcranial photobiomodulation with near‐infrared light on sexual dysfunction
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Flsm.23011
https://www.ncbi.nlm.nih.gov/pubmed/30221776
https://www.proquest.com/docview/2333931049
https://www.proquest.com/docview/2108245342
https://pubmed.ncbi.nlm.nih.gov/PMC6382556
Volume 51
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ1ba9VAEMeHUijog9Z6i1ZZxQdf0p7sbjZZfBKxFLE-qIWCQsheQounSWlyHtonP0I_Yz-JM5tLe6yC-HI4sBNOLjM7_8yZ_S3AK8z52jiq3FdaxJhvbawrqeK0lDPHlXVJKOjvfVK7-_LDQXqwAm_GtTA9H2IquFFkhPmaArw07fYVNHTeHlMXc1jXS71aJIg-X6GjBB-XShNwV_ORKjTj29ORy7nohsC82Sd5Xb-GBLRzF76Pp973nfzYWnRmy57_RnX8z2tbhzuDMGVve0-6Byu-3oDb13CFG7AW2kVtex--9dDjljUV6yjbWfxAT2Ynh01HYKfjxg37gjGq9LIaA-ry5wW68yl1vLM51QQYjrYB-czcWUsZlg54APs777--242HbRpiK3GqjHXuUnoRy0ruU1qAJUQpeVlpkymVE-LdCJeYzGW5ltbiqM0NYdmkS53UlXgIq3VT-8fApEo96pHEe4WTi1N5olyeeW2kSbiXswhejw-ssAPDnLbSmBc9fZkXeOeKcOcieDmZnvTgjj8ZbY5PvRhit8URITSqXqkjeDENY9TRXyll7ZsF2iQonWQqJI_gUe8k068IlEVJlqkIsiX3mQyI6L08Uh8dBrI3ToaEhMPLDN7x9xMvPn7ZC1-e_LvpU7iFak_3LeebsNqdLvwzVFSdeR5C5xfFbx14
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ1Lb9QwEIBHVRECDjwKhUABgzhwSbuxnYclLghRLbDbA7RSJYSi-BEVsU2qJnuAEz-B38gvYcZ5tEtBQlyilWaiPDzjmcyOPwM8w5ivtKXKfalEiPHWhKqUSRgXcmJ5YmzkC_rzvWR6IN8exodr8GJYC9PxIcaCG3mGn6_JwakgvXNGDV00x9TGTAt7L9GO3v6D6v0ZPErwYbE0IXcVH7hCE74znroajS6kmBc7Jc9nsD4E7d6AT8PNd50nX7aXrd42337jOv7v092E631uyl52xnQL1ly1AdfOEQs34LLvGDXNbfjYcY8bVpespYBn8IDGzE6O6pbYTse17bcGY1TsZRX61M_vP9CiT6npnS2oLMBQ2njqM7NfGwqydMIdONh9vf9qGvY7NYRG4mwZqszG9C2WFtzFtAZLiELyolQ6TZKMKO9a2EinNs2UNAalJtNEZpM2tlKVYhPWq7py94DhSDpMSSLnEpxfbJJFic1Sp7TUEXdyEsDzYcRy02PMaTeNRd4BmHmOby73by6Ap6PqScfu-JPS1jDsee--DUqEUJj4ShXAk1GMjkf_phSVq5eoE2H2JGMheQB3OysZryIwM4rSNAkgXbGfUYGg3quS6vORh3vjfEhUOHxMbx5_v_F89mHuf9z_d9XHcGW6P5_lszd77x7AVUz-VNeBvgXr7enSPcQEq9WPvB_9AnxfIZM
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ1Lb9QwEMdHVREIDjzKK1DAIA5c0m5sx4nFCQGrAm2FgEqVQIoS21GrbpNVkz3AiY_AZ-STMOM82qUgIS6rlTxRXjOe_86OfwZ4ijlfF5Yq96UWIeZbE-pSqjDO5cRyZWzkC_o7u2prT77dj_dX4PmwFqbjQ4wFN4oMP19TgM9tuXkKDZ01x9TFTOt6L0iFpyRF9OGUHSX4sFaaiLuaD1ihCd8cD11ORucU5vlGybMC1meg6TX4Mlx713hytLFoiw3z7Tes43_e3HW42itT9qJzpRuw4qo1uHKGV7gGF32_qGluwueOetywumQtpTuDH-jKbH5Qt0R2Oq5tvzEYo1IvqzCifn7_gf58Qi3vbEZFAYajjWc-M_u1oRRLB9yCvenrTy-3wn6fhtBInCtDndqYfoklOXcxrcASIpc8L3WRKJUS470QNioSm6RaGoOjJi2IyyZtbKUuxW1YrerK3QUmVexQkETOKZxdrEojZdPE6UIWEXdyEsCz4YVlpoeY014as6zDL_MMn1zmn1wAT0bTeUfu-JPR-vDWsz54GxwRQqPslTqAx-Mwhh39l5JXrl6gTYTaScZC8gDudE4ynkWgLoqSRAWQLLnPaEBI7-WR6vDAo71xNiQmHN6m946_X3i2_XHHf7n376aP4NL7V9Ns-83uu_twGZWf7trP12G1PVm4B6iu2uKhj6JfJPUgSw
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effects+of+transcranial+photobiomodulation+with+near-infrared+light+on+sexual+dysfunction&rft.jtitle=Lasers+in+surgery+and+medicine&rft.au=Cassano%2C+Paolo&rft.au=Dording%2C+Christina&rft.au=Thomas%2C+Garrett&rft.au=Foster%2C+Simmie&rft.date=2019-02-01&rft.eissn=1096-9101&rft.volume=51&rft.issue=2&rft.spage=127&rft_id=info:doi/10.1002%2Flsm.23011&rft_id=info%3Apmid%2F30221776&rft.externalDocID=30221776
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0196-8092&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0196-8092&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0196-8092&client=summon