Mutations at protein-protein interfaces: Small changes over big surfaces have large impacts on human health - Jubb, Harry C.; Pandurangan, Arun P.; Turner, Meghan A.; Ochoa-Montaño, Bernardo; Blundell, Tom L.; Ascher, David B. (Progress in biophysics and molecular biology, 2017)
Keywords: Drug development; Genetic Diseases, Inborn - drug therapy; Genetic Diseases, Inborn - genetics; Genetic Diseases, Inborn - metabolism; Health; Humans; Molecular Targeted Therapy; Mutation; Mutations; Protein Binding - genetics; Protein interaction; Protein stability; Protein-protein interfaces; Proteins - chemistry; Proteins - genetics; Proteins - metabolism; Mutations; Protein stability; Drug development; Protein interaction; Protein-protein interfaces