Cyclin-dependent kinase-specific activity predicts the prognosis of stage I and stage II non-small cell lung cancer

• Published in: BMC cancer Vol. 14; no. 1; p. 755
• Main Authors: Kubo, Hiroshi, Suzuki, Takashi, Matsushima, Tomoko, Ishihara, Hideki, Uchino, Kazuya, Suzuki, Satoshi, Tada, Sachiyo, Yoshimura, Masahiro, Kondo, Takashi
• Format: Journal Article
• Language: English
• Published: England BioMed Central 09.10.2014
• Subjects: Aged; Aged, 80 and over; Breast cancer; Cancer therapies; Carcinoma, Non-Small-Cell Lung - metabolism; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - pathology; Chemotherapy; Cohort Studies; Cyclin-Dependent Kinases - metabolism; Female; Follow-Up Studies; Humans; Lung cancer; Lung Neoplasms - metabolism; Lung Neoplasms - mortality; Lung Neoplasms - pathology; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Proportional Hazards Models; ROC Curve; Japan

Lung cancer is one of the leading causes of cancer death worldwide. Even with complete resection, the prognosis of early-stage non-small cell lung cancer is poor due to local and distant recurrence, and it remains unclear which biomarkers are clinically useful for predicting recurrence or for determ...