Long-term outcomes during treatment of chronic pain with intrathecal clonidine or clonidine/opioid combinations

• Published in: Journal of pain and symptom management Vol. 26; no. 1; pp. 668 - 677
• Main Authors: Ackerman, Laurie L., Follett, Kenneth A., Rosenquist, Richard W.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2003; Elsevier Science
• Subjects: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics - administration & dosage; Analgesics - adverse effects; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - adverse effects; Biological and medical sciences; Chronic Disease; chronic pain; Clonidine; Clonidine - administration & dosage; Clonidine - adverse effects; Drug Therapy, Combination; Female; Humans; Hydromorphone - administration & dosage; Hydromorphone - adverse effects; Infusion Pumps, Implantable; Injections, Spinal; intrathecal; Male; Medical sciences; Middle Aged; Neuropharmacology; opioids; Pain - drug therapy; Pharmacology. Drug treatments; polyanalgesia; Treatment Outcome; intrathecal; chronic pain; Clonidine; polyanalgesia; opioids; Human; Imidazole derivatives; Drug combination; Toxicity; Treatment efficiency; Opiates; Intrathecal administration; Chemotherapy; Chronic; Pain; Treatment

To evaluate the effectiveness of intrathecal clonidine or clonidine/opioid admixture for the treatment of chronic pain states, a retrospective chart audit of 15 patients seen by the Pain Medicine and Neurosurgical Services was performed. Subjects included 9 men and 6 women aged 26–86 years. Diagnose...