Low Serum Phosphorus Correlates with Cerebral Aβ Deposition in Cognitively Impaired Subjects: Results from the KBASE Study

• Published in: Frontiers in aging neuroscience Vol. 9; p. 362
• Main Authors: Park, Jong-Chan, Han, Sun-Ho, Byun, Min S., Yi, Dahyun, Lee, Jun Ho, Park, Kyua, Lee, Dong Young, Mook-Jung, Inhee
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 06.11.2017; Frontiers Media S.A
• Subjects: Age; Aluminum; Alzheimer's disease; Apolipoprotein E; Biomarkers; Brain research; Calcium; Cognitive ability; Dementia; Dementia disorders; Genotypes; Geriatrics; KBASE; Medicine; Memory; mild cognitive impairment; Neurodegeneration; Neurodegenerative diseases; Neuroscience; NMR; Nuclear magnetic resonance; Pathogenesis; Peptides; Phosphorus; PiB-PET; Positron emission tomography; Serum levels; β-Amyloid; United States > US; South Korea; Pittsburgh Pennsylvania; blood-based biomarker; KBASE; mild cognitive impairment; PiB-PET; Alzheimer's disease; phosphorus; β-amyloid

Alzheimer's disease (AD), characterized by progressive cognitive decline, is the most prevalent neurodegenerative disease in the elderly. Cerebral β-amyloid (Aβ) deposition is the major pathological hallmark of AD. Recent studies also have shown that the serum level of phosphorus correlates to...