The cell cycle: a review

• Published in: Veterinary pathology Vol. 35; no. 6; pp. 461 - 478
• Main Author: Schafer, K.A. (Wyeth-Ayerst Research, Chazy, NY.)
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.11.1998
• Subjects: Adenoviridae; ADN; animal pathology; Animals; cell cycle; Cell Cycle - physiology; Cell Cycle Proteins - physiology; cyclin-dependent kinase; cyclins; DNA; DNA MODIFICATION; DRUGS; GENETIC REGULATION; GENETICA; GENETICS; GENETIQUE; Humans; LITERATURE REVIEWS; MEDICAMENT; MEDICAMENTOS; MITOSE; MITOSIS; NEOPLASMAS; NEOPLASME; NEOPLASMS; oncogenes; Papillomaviridae; PATHOGENESE; PATHOGENESIS; PATOGENESIS; Polyomaviridae; PROTEIN KINASE; PROTEINA QUINASA; PROTEINAS; PROTEINE; PROTEINE KINASE; PROTEINS; REGULATION; TOXICOLOGIA; TOXICOLOGIE; TOXICOLOGY; TOXINAS; TOXINE; TOXINS; TRANSCRIPCION; TRANSCRIPTION; transcription (genetics); tumor suppressor genes; VIROLOGIA; VIROLOGIE; VIROLOGY; VIRUS; VIRUSES; toxicology; retinoblastoma protein; cyclin-dependent kinases; cell cycle; virology; cyclins; p53 protein; Cancer

The cell cycle is a complex process that involves numerous regulatory proteins that direct the cell through a specific sequence of events culminating in mitosis and the production of two daughter cells. Central to this process are the cyclin-dependent kinases (cdks), which complex with the cyclin pr...