The effect of maternal obstructive sleep apnea on the placenta

• Published in: Sleep (New York, N.Y.) Vol. 42; no. 6; p. 1
• Main Authors: Kidron, Debora, Bar-Lev, Yamit, Tsarfaty, Ilan, Many, Ariel, Tauman, Riva
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 11.06.2019
• Subjects: Adiposity; Adult; Analysis; Apnea; Biochemistry; Birth Weight - physiology; Body Mass Index; Clinical trials; Endothelial growth factors; Female; Fetal development; Gene expression; Genes; Genetic research; Health risk assessment; Humans; Infant, Newborn; Leptin; Leptin - metabolism; Longitudinal Studies; Medical research; Newborn infants; Obesity - complications; Placenta; Placenta - physiology; Placentation - physiology; Pregnancy; Prenatal development; Prospective Studies; Respiration disorders; RNA; Sleep apnea; Sleep Apnea, Obstructive - physiopathology; Vascular endothelial growth factor; Women; Israel; obstructive sleep apnea; sleep-disordered breathing; fetal growth; pregnancy

Obstructive sleep apnea (OSA) during pregnancy has been associated with adverse maternal outcomes. However, the effect of maternal OSA on fetal growth is less clear. The placenta is a critical organ for fetal growth and development and the principal determinant of birthweight. We aimed to investigat...