Nodal Global Efficiency in Front-Parietal Lobe Mediated Periventricular White Matter Hyperintensity (PWMH)-Related Cognitive Impairment

• Published in: Frontiers in aging neuroscience Vol. 11; p. 347
• Main Authors: Chen, Haifeng, Huang, Lili, Yang, Dan, Ye, Qing, Guo, Mengdi, Qin, Ruomeng, Luo, Caimei, Li, Mengchun, Ye, Lei, Zhang, Bing, Xu, Yun
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 10.12.2019; Frontiers Media S.A
• Subjects: cingulo-opercular network; Cognition & reasoning; Cognitive ability; cognitive impairment; Dementia; Dementia disorders; Education; Efficiency; fronto-parietal network; functional efficiency; Geriatrics; Hospitals; Information processing; Laboratories; Medical imaging; Neuroscience; Parietal lobe; Substantia alba; white matter hyperintensity; China; functional efficiency; cognitive impairment; fronto-parietal network; cingulo-opercular network; white matter hyperintensity

White matter hyperintensity (WMH) is widely observed in the elderly population and serves as a key indicator of cognitive impairment (CI). However, the underlying mechanism remains to be elucidated. Herein, we investigated the topological patterns of resting state functional networks in WMH subjects...