The impact of HIV infection on skeletal maturity in peripubertal children in Zimbabwe: a cross-sectional study

• Published in: BMC pediatrics Vol. 24; no. 1; pp. 480 - 12
• Main Authors: Kowo-Nyakoko, Farirayi, Gregson, Celia L., Westbury, Leo D., Madanhire, Tafadzwa, Offiah, Amaka C., Micklesfield, Lisa K., Ferrand, Rashida Abbas, Rehman, Andrea M., Ward, Kate A.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.07.2024; BioMed Central; BMC
• Subjects: Adolescence; Adolescent; Africa; Age; Age Determination by Skeleton; Anti-HIV Agents - therapeutic use; Antiretroviral drugs; Antiviral agents; Body mass index; Bone age; Bone Development - drug effects; Bones; Case-Control Studies; Child; Child development; Children; Children & youth; Cross-Sectional Studies; Density; Dosage and administration; Exercise; Female; Girls; Health aspects; HIV; HIV infection; HIV Infections - drug therapy; Hospitals; Households; Human immunodeficiency virus; Humans; Infections; Male; Pediatrics; Penis; Prevention; Puberty; Questionnaires; Risk Factors; Socioeconomic factors; Teenagers; Tenofovir - therapeutic use; Vitamin D; Zimbabwe - epidemiology; Zimbabwe; United States > US; Africa; Adolescence; Puberty; Children; HIV; Bone age; Africa

HIV infection and its treatment compromises skeletal development (growth and maturation). Skeletal maturity is assessed as bone age (BA) on hand and wrist radiographs. BA younger than chronological age (CA) indicates delayed development. We conducted a cross-sectional study to determine differences...