Dynamics of the preterm gut microbiome in health and disease

• Published in: American journal of physiology: Gastrointestinal and liver physiology Vol. 320; no. 4; pp. G411 - G419
• Main Authors: Cuna, Alain, Morowitz, Michael J., Ahmed, Ishfaq, Umar, Shahid, Sampath, Venkatesh
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.04.2021
• Series: Microbiome and Host Interactions
• Subjects: Animals; Asthma; Atopy; Bacteria - growth & development; Digestive system; Disease; Dysbacteriosis; Dysbiosis; Enterocolitis, Necrotizing - microbiology; Enterocolitis, Necrotizing - therapy; Environmental factors; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Gastrointestinal tract; Gestational Age; Gut microbiota; Host-Pathogen Interactions; Humans; Infant, Newborn; Infant, Premature; Infants; Intestinal microflora; Intestine; Intestines - microbiology; Metagenomics; Microbiomes; Mini-Review; Necrotizing enterocolitis; Neonatal Sepsis - microbiology; Neonatal Sepsis - therapy; Neonates; Newborn babies; Prebiotics; Probiotics; Probiotics - therapeutic use; Prognosis; Reviews; Risk Factors; Sepsis; preterm; necrotizing enterocolitis; gut microbiome; sepsis; dysbiosis

Advances in metagenomics have allowed a detailed study of the gut microbiome, and its role in human health and disease. Infants born prematurely possess a fragile gut microbial ecosystem that is vulnerable to perturbation. Alterations in the developing gut microbiome in preterm infants are linked to...