Altered Expression Profile of IgLON Family of Neural Cell Adhesion Molecules in the Dorsolateral Prefrontal Cortex of Schizophrenic Patients

• Published in: Frontiers in molecular neuroscience Vol. 11; p. 8
• Main Authors: Karis, Karina, Eskla, Kattri-Liis, Kaare, Maria, Täht, Karin, Tuusov, Jana, Visnapuu, Tanel, Innos, Jürgen, Jayaram, Mohan, Timmusk, Tõnis, Weickert, Cynthia S., Väli, Marika, Vasar, Eero, Philips, Mari-Anne
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 29.01.2018; Frontiers Media S.A
• Subjects: Axonogenesis; Brain research; Cannabis; Cell adhesion & migration; Cell adhesion molecules; Cortex (frontal); Gene expression; Genomes; Genomics; Medicine; Mental disorders; Meta-analysis; Neural networks; Neuroscience; Prefrontal cortex; Proteins; Psychiatry; Risk factors; Schizophrenia; Studies; Suicides & suicide attempts; Synaptic plasticity; Transcription; Australia; Estonia

Neural adhesion proteins are crucial in the development and maintenance of functional neural connectivity. Growing evidence suggests that the IgLON family of neural adhesion molecules LSAMP, NTM, NEGR1, and OPCML are important candidates in forming the susceptibility to schizophrenia (SCZ). IgLON pr...