Sex Differences in Abnormal Intrinsic Functional Connectivity After Acute Mild Traumatic Brain Injury

• Published in: Frontiers in neural circuits Vol. 12; p. 107
• Main Authors: Wang, Shan, Hu, Liuxun, Cao, Jieli, Huang, Wenmin, Sun, Chuanzhu, Zheng, Dongdong, Wang, Zhuonan, Gan, Shuoqiu, Niu, Xuan, Gu, Chenghui, Bai, Guanghui, Ye, Limei, Zhang, Danbin, Zhang, Nu, Yin, Bo, Zhang, Ming, Bai, Lijun
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 29.11.2018; Frontiers Media S.A
• Subjects: Adult; Brain - diagnostic imaging; Brain - physiopathology; Brain Concussion - diagnostic imaging; Brain Concussion - physiopathology; Brain research; Cerebellum; Concussion; Executive function; Executive Function - physiology; Female; Females; functional connectivity; Gender differences; Gene expression; Health care; Hospitals; Humans; independent component analysis; Male; Males; Medical imaging; Middle Aged; mild traumatic brain injury; Nerve Net - diagnostic imaging; Nerve Net - physiopathology; Neural networks; Neuroscience; Post traumatic stress disorder; Recombination; rs-fMRI; Sex Characteristics; sex difference; Sex differences; Sleep disorders; Statistical analysis; Studies; Task forces; Trauma; Traumatic brain injury; Young Adult; China; independent component analysis; functional connectivity; sex difference; mild traumatic brain injury; rs-fMRI

Mild traumatic brain injury (TBI) is considered to induce abnormal intrinsic functional connectivity within resting-state networks (RSNs). The objective of this study was to estimate the role of sex in intrinsic functional connectivity after acute mild TBI. We recruited a cohort of 54 patients (27 m...