CYP-mediated resistance and cross-resistance to pyrethroids and organophosphates in Aedes aegypti in the presence and absence of kdr

• Published in: Pesticide Biochemistry and Physiology Vol. 160; pp. 119 - 126
• Main Authors: Smith, Letícia B., Sears, Colin, Sun, Haina, Mertz, Robert W., Kasai, Shinji, Scott, Jeffrey G.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2019; Elsevier BV
• Subjects: additive effect; Aedes; Aedes - drug effects; Aedes aegypti; Animals; Cross-resistance; cyfluthrin; Cytochrome P-450 Enzyme System; Cytochrome P-450 Enzyme System - metabolism; Cytochrome P450 monooxygenase; etofenprox; Female; fenitrothion; Gene Knockdown Techniques; Insecticide Resistance; Insecticide Resistance - genetics; Male; Mutation; naled; Organophosphate; Organophosphates; Organophosphates - pharmacology; paraoxon; parathion-methyl; Pyrethrins; Pyrethrins - pharmacology; Pyrethroid; resistance mechanisms; sodium channels; urban areas; viral diseases of animals and humans; Pyrethroid; Aedes aegypti; Insecticide resistance; Organophosphate; Cross-resistance; Cytochrome P450 monooxygenase
• ISSN: 0048-3575; 1095-9939; 1095-9939
• DOI: 10.1016/j.pestbp.2019.07.011

Aedes aegypti thrives in urban environments and transmits several debilitating human viral diseases. Thus, our ability to control this mosquito species in endemic areas is of utmost importance. The use of insecticides, mostly pyrethroids and organophosphates (OPs), has long been the primary means of...