Serum miRNAs Expression and SNAP-25 Genotype in Alzheimer’s Disease

• Published in: Frontiers in aging neuroscience Vol. 11; p. 52
• Main Authors: Agostini, Simone, Mancuso, Roberta, Liuzzo, Gaia, Bolognesi, Elisabetta, Costa, Andrea Saul, Bianchi, Anna, Clerici, Mario
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 11.03.2019; Frontiers Media S.A
• Subjects: 3' Untranslated regions; Alzheimer's disease; Atrophy; Biomarkers; Brain; Cognitive ability; Dementia; Dementia disorders; Disease; Exocytosis; Gene expression; Gene polymorphism; Genotype & phenotype; genotyping; Laboratories; Memory; microRNA; MicroRNAs; mild cognitive impairment; miRNA; N-Ethylmaleimide-sensitive protein; Neurological disorders; Neuroplasticity; Neuroscience; Neurotransmitters; NMR; Non-coding RNA; Nuclear magnetic resonance; Polymorphism; Proteins; Rehabilitation; SNAP receptors; SNAP-25; SNAP-25 protein; SNP; Stroke; Vitamin deficiency; Italy; microRNA; mild cognitive impairment; Alzheimer’s disease; SNP; SNAP-25; genotyping

MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression by binding their 3' untranslated region (3'UTR) region; these molecules play a fundamental role in several pathologies, including Alzheimer's disease (AD). Synaptosomal-associated protein of 25 kDa (SNAP-25) is...