Case-Control Study of the Effects of Gut Microbiota Composition on Neurotransmitter Metabolic Pathways in Children With Attention Deficit Hyperactivity Disorder

• Published in: Frontiers in neuroscience Vol. 14; p. 127
• Main Authors: Wan, Lin, Ge, Wen-Rong, Zhang, Shan, Sun, Yu-Lin, Wang, Bin, Yang, Guang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 18.02.2020; Frontiers Media S.A
• Subjects: Age; Attention deficit hyperactivity disorder; Body mass index; child; Children; Deoxyribonucleic acid; DNA; Dopamine; Families & family life; gastrointestinal microbiome; Genes; Genomes; Hyperactivity; Intestinal microflora; Mental disorders; Metabolic pathways; Metabolism; Metabolites; Metagenomics; Microbiomes; Microbiota; Neuroscience; neurotransmitter; Neurotransmitters; Pathogenesis; Pediatrics; Phylogenetics; Principal components analysis; Serotonin; shotgun metagenomics sequencing; Studies; Variance analysis; Vegetarianism; United States > US; shotgun metagenomics sequencing; attention deficit hyperactivity disorder; neurotransmitter; gastrointestinal microbiome; child

Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric condition that may be related to an imbalance of neural transmitters. The gut microbiota is the largest ecosystem in the human body, and the brain-gut axis theory proposes that the gut microbiome can affect brain function in multi...