Deregulatory miRNA-BDNF Network Inferred from Dynamic Expression Changes in Schizophrenia

• Published in: Brain sciences Vol. 12; no. 2; p. 167
• Main Authors: Fu, Xiaoqian, Liu, Yansong, Baranova, Ancha, Zhang, Fuquan
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 27.01.2022; MDPI
• Subjects: Brain-derived neurotrophic factor; co-expression analyses; Communication; Disease; Gene expression; Kinases; Mental disorders; miR-124-3p; miR-132-3p; miR-206; miRNA; mRNA; Patients; Peripheral blood; Psychiatrists; Psychotropic drugs; Schizophrenia; Suicides & suicide attempts; United States > US; co-expression analyses; miR-132-3p; brain-derived neurotrophic factor; miR-124-3p; schizophrenia; miR-206

(1) Background: Brain-derived neurotrophic factor (BDNF) is one of the promising risk genes for schizophrenia (SZ), a disease with prominent dysregulation of miRNA networks. Here, we present a study of miRNA-BDNF co-expression changes in peripheral blood of SZ patients. (2) Methods: The expression l...