Whole brain myelin mapping using T1- and T2-weighted MR imaging data

• Published in: Frontiers in human neuroscience Vol. 8; p. 671
• Main Authors: Ganzetti, Marco, Wenderoth, Nicole, Mantini, Dante
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 02.09.2014; Frontiers Media S.A
• Subjects: Aging; Anisotropy; brain integrity assessment; Brain Mapping; Cortex; Magnetic Resonance Imaging; Multiple sclerosis; Myelin; myelin enhanced contrast; Neuroimaging; Neuroscience; NMR; Nuclear magnetic resonance; Statistical analysis; brain mapping; myelin enhanced contrast; myelin mapping; magnetic resonance imaging; brain integrity assessment

Despite recent advancements in MR imaging, non-invasive mapping of myelin in the brain still remains an open issue. Here we attempted to provide a potential solution. Specifically, we developed a processing workflow based on T1-w and T2-w MR data to generate an optimized myelin enhanced contrast ima...