Red blood cell transfusion is associated with decreased in-hospital muscle strength among critically ill patients requiring mechanical ventilation

• Published in: Journal of critical care Vol. 28; no. 6; pp. 1079 - 1085
• Main Authors: Parsons, Elizabeth C., Kross, Erin K., Ali, Naeem A., Vandevusse, Lisa K., Caldwell, Ellen S., Watkins, Timothy R., Heckbert, Susan R., Hough, Catherine L.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2013; Elsevier Limited
• Subjects: APACHE; Blood; Blood platelets; Body mass index; Chronic illnesses; Critical Care; Critical Illness; Erythrocyte transfusion; Erythrocyte Transfusion - adverse effects; Female; Hand Strength; Hospitalization; Hospitals; Humans; Intensive care; Length of Stay - statistics & numerical data; Male; Middle Aged; Muscle weakness; Older people; Organ Dysfunction Scores; Prospective Studies; Respiration, Artificial; Respiratory distress syndrome; Risk Factors; Studies; Ventilation; Ventilators; Intensive care; Muscle weakness; Hand strength; Respiratory distress syndrome; Erythrocyte transfusion

Red blood cell (RBC) transfusion is linked to poor functional recovery after surgery and trauma. To investigate one potential mechanism, we examined the association between RBC transfusion and muscle strength in a cohort of critically ill patients. We performed a secondary analysis of 124 critically...