Pharmacokinetics and Dose Proportionality Study of a Novel Antiparkinsonian Agent, a 1H-1,2,4-Triazol-3-ylthio-conjugate of Prottremine - Gorina, Daria S.; Lastovka, Anastasiya V.; Rogachev, Artem D.; Podturkina, Alexandra V.; Pavlova, Alla V.; Ardashov, Oleg V.; Li-Zhulanov, Nikolai S.; Tolstikova, Tatyana G.; Volcho, Konstantin P.; Salakhutdinov, Nariman F. (Molecules (Basel, Switzerland), 2024)
Keywords: Acids; Antiparkinsonian agents; Bioavailability; Brain research; Chromatography; Clinical trials; Disease; Dopamine; dose proportionality; Drug dosages; LC–MS/MS; Metabolism; Nervous system diseases; Parkinson’s disease; pharmacokinetic; Pharmacokinetics; Solvents; Toxicity; validation; Germany; Russia