A System-Based Comparison of Gene Expression Reveals Alterations in Oxidative Stress, Disruption of Ubiquitin-Proteasome System and Altered Cell Cycle Regulation after Exposure to Cadmium and Methylmercury in Mouse Embryonic Fibroblast - Yu, Xiaozhong; Robinson, Joshua F.; Sidhu, Jaspreet S.; Hong, Sungwoo; Faustman, Elaine M. (Toxicological sciences, 2010)
Keywords: Animals; Cadmium Chloride - toxicity; Cell Cycle; Cell Cycle Proteins - drug effects; cell cycle regulation; Cell Line; Cell Survival - drug effects; Comparative Genomic Hybridization; Cysteine Proteinase Inhibitors - pharmacology; Environmental Pollutants - toxicity; Fibroblasts - drug effects; Fibroblasts - pathology; Gene Expression Profiling; Gene Expression Regulation, Enzymologic - drug effects; Leupeptins - pharmacology; metals; Methylmercury Compounds - toxicity; Mice; Microarray Analysis; oxidative stress; Oxidative Stress - drug effects; Proteasome Endopeptidase Complex - drug effects; Proteasome Endopeptidase Complex - metabolism; Proteasome Inhibitors; Systems Toxicology; ubiquitin-proteasome pathway; Ubiquitins - metabolism