A Purely Biomanufactured System for Delivering Nanoparticles and STING Agonists

• Published in: Advanced science Vol. 12; no. 3; pp. e2408539 - n/a
• Main Authors: Li, Yu‐an, Feng, Yi, Li, Wenjing, Zhang, Yuqin, Sun, Yanni, Wang, Shifeng, Curtiss, Roy, Shi, Huoying
• Format: Journal Article
• Language: English
• Published: Germany John Wiley & Sons, Inc 01.01.2025; John Wiley and Sons Inc; Wiley
• Subjects: Adjuvants; Animals; Antigens; Bacteria; Biosynthesis; Cholera; Cytoplasm; Drug Delivery Systems - methods; Efficiency; Gram-positive bacteria; Humans; Immune system; Immunity (Disease); Localization; Membrane Proteins - agonists; Membranes; Mice; nanoparticle; Nanoparticles; Nanoparticles - administration & dosage; Nanoparticles - chemistry; Peptides; Plasmids; Proteins; purely biological system; Salmonella; STING agonist; Toxins; Transmission electron microscopy; universal vaccine; Vaccines; Vaccines - immunology; nanoparticle; universal vaccine; STING agonist; purely biological system

Nanovaccines have significantly contributed in the prevention and treatment of diseases. However, most of these technologies rely on chemical or hybrid semibiological synthesis methods, which limit the manufacturing performance advantages and improved inoculation outcomes compared with traditional v...