Depressive symptoms increase the risk of progression to dementia in subjects with mild cognitive impairment: systematic review and meta-analysis

• Published in: International journal of geriatric psychiatry Vol. 31; no. 8; pp. 905 - 911
• Main Authors: Mourao, Raimundo J., Mansur, Guilherme, Malloy-Diniz, Leandro F., Castro Costa, Erico, Diniz, Breno S.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.08.2016; Wiley Subscription Services, Inc
• Subjects: Aged; Alzheimer's disease; Cognition & reasoning; Cognitive Dysfunction - epidemiology; Comorbidity; Dementia; Dementia - epidemiology; depression; Depression - epidemiology; Disease Progression; Geriatric psychiatry; Geriatric psychology; Humans; Mental depression; Meta-analysis; mild cognitive impairment; Risk Factors; Systematic review; meta-analysis; dementia; mild cognitive impairment; depression; Alzheimer's disease

Objective There is a long‐standing debate in the literature whether depressive symptoms increase the risk of dementia in older with mild cognitive impairment (MCI). We aim to conduct a meta‐analysis of studies that evaluated the risk of dementia in subjects with MCI and depressive symptoms compared...