Ocular myasthenia gravis in a senior population: Diagnosis, therapy, and prognosis

• Published in: Muscle & nerve Vol. 41; no. 3; pp. 379 - 384
• Main Authors: Allen, Jeffrey A., Scala, Stephanie, Jones, H. Royden
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.03.2010; Wiley
• Subjects: Age Factors; Age of Onset; Aged; Aged, 80 and over; Azathioprine - therapeutic use; Biological and medical sciences; Chi-Square Distribution; Cyclosporine - therapeutic use; Disease Progression; Disease-Free Survival; Diseases of striated muscles. Neuromuscular diseases; Electric Stimulation; Electromyography; Female; Humans; Immunotherapy; late onset; Male; Medical sciences; Muscle; myasthenia gravis; Myasthenia Gravis - diagnosis; Myasthenia Gravis - immunology; Myasthenia Gravis - therapy; Neurology; ocular; Patient Selection; Pharmacology. Drug treatments; Plasma Exchange; Prednisone - therapeutic use; Prognosis; Remission Induction; Retrospective Studies; Severity of Illness Index; Thymectomy; treatment; Treatment Outcome; Human; Nervous system diseases; Neuromuscular diseases; Feeding behavior; Prognosis; Retrospective; Feeding; ocular; Myasthenia gravis; Treatment; Immunotherapy; Repetitive stimulus; Sign; Diagnosis; late onset; Biological receptor

The objectives of this study were (I) to explore the prognosis of ocular myasthenia gravis (OMG) in patients with onset at age 70 years and above (i.e. senior persons); (2) to identify predictors of secondary generalization in this age group; and 3) to address the effects of immunotherapy on this po...