Evaluation of the Pig-a, micronucleus, and comet assay endpoints in a 28-day study with ethyl methanesulfonate - Gunther, William C.; Coffing, Stephanie L.; Dickinson, Donna A.; Engel, Maria E.; Fiedler, Ronald D.; O'Lone, Susan D.; Sanok, Kelley E.; Thiffeault, Catherine J.; Shutsky, Thomas J.; Schuler, Maik J.; Dobo, Krista L. (Environmental and molecular mutagenesis, 2014)
Keywords: Animals; Bioassays; Colon - cytology; Colon - drug effects; Comet Assay - methods; DNA Damage - drug effects; Dose-Response Relationship, Drug; Endpoint Determination; Erythrocytes - drug effects; Ethyl Methanesulfonate - toxicity; Genotoxicity; in vivo genotoxicity; in vivo mutation assay; integration; Liver - cytology; Liver - drug effects; Male; Membrane Proteins - drug effects; Membrane Proteins - genetics; Micronucleus Tests - methods; Mutation Rate; Rats; Rats, Sprague-Dawley; Reticulocytes - drug effects; Swine; integration; in vivo mutation assay; in vivo genotoxicity