Lactate infusion at rest increases BDNF blood concentration in humans

• Published in: Neuroscience letters Vol. 488; no. 3; pp. 234 - 237
• Main Authors: Schiffer, Thorsten, Schulte, Stefanie, Sperlich, Billy, Achtzehn, Silvia, Fricke, Hannes, Strüder, Heiko K.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 25.01.2011; Elsevier
• Subjects: Acidosis; Adult; Alkalosis; Biological and medical sciences; Brain-Derived Neurotrophic Factor - blood; Enzyme-Linked Immunosorbent Assay; Exercise - physiology; Fundamental and applied biological sciences. Psychology; Humans; Infusions, Intravenous; Lactic Acid - administration & dosage; Lactic Acid - blood; Male; Neurotrophins; Rest; Sodium-lactate; Vertebrates: nervous system and sense organs; Sodium-lactate; Neurotrophins; Acidosis; Alkalosis; Human; Neurotrophin; Lactates; Metabolic disorder; Sodium; Acid base balance disorder; Brain derived neurotrophic factor

▶ Blood lactate is involved in the regulation of BDNF blood concentrations. ▶ Strengthening the assumption that high intensity exercise increases BDNF in blood. ▶ The lactate clamp can be used to examine BDNF responses in healthy humans. Studies in humans use blood lactate to determine the degree of...