Novel antiplatelet drugs in clinical development
The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold prom...
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Published in | Thrombosis and haemostasis Vol. 110; no. 5; p. 868 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Germany
01.11.2013
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Subjects | |
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Abstract | The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold promise to improve this benefit-risk ratio. |
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AbstractList | The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold promise to improve this benefit-risk ratio. |
Author | Ungerer, M Münch, G |
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CitedBy_id | crossref_primary_10_1016_j_fitote_2020_104709 crossref_primary_10_1002_cmdc_201700522 crossref_primary_10_1016_j_prostaglandins_2019_106353 crossref_primary_10_1161_ATVBAHA_114_303413 crossref_primary_10_3390_biomedicines12122855 crossref_primary_10_1007_s11883_015_0501_1 crossref_primary_10_1016_j_pharmthera_2018_08_004 crossref_primary_10_1016_j_bmc_2015_03_075 crossref_primary_10_1161_JAHA_117_005991 crossref_primary_10_1016_j_bmcl_2016_04_009 crossref_primary_10_1097_FJC_0000000000000269 crossref_primary_10_1160_TH13_09_0805 crossref_primary_10_1016_j_vph_2017_01_003 crossref_primary_10_1051_medsci_20153108006 crossref_primary_10_1080_09537104_2016_1212001 crossref_primary_10_3390_cancers10080253 crossref_primary_10_1007_s10529_017_2346_x |
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SubjectTerms | Animals Cerebrovascular Disorders - drug therapy Clinical Trials as Topic Drug Discovery Humans Platelet Aggregation Inhibitors - pharmacology Platelet Aggregation Inhibitors - therapeutic use Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors Purinergic P2Y Receptor Antagonists - therapeutic use Receptor, PAR-1 - antagonists & inhibitors Risk Assessment |
Title | Novel antiplatelet drugs in clinical development |
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