Novel antiplatelet drugs in clinical development

The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold prom...

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Published inThrombosis and haemostasis Vol. 110; no. 5; p. 868
Main Authors Ungerer, M, Münch, G
Format Journal Article
LanguageEnglish
Published Germany 01.11.2013
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Abstract The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold promise to improve this benefit-risk ratio.
AbstractList The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold promise to improve this benefit-risk ratio.
Author Ungerer, M
Münch, G
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Snippet The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they...
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StartPage 868
SubjectTerms Animals
Cerebrovascular Disorders - drug therapy
Clinical Trials as Topic
Drug Discovery
Humans
Platelet Aggregation Inhibitors - pharmacology
Platelet Aggregation Inhibitors - therapeutic use
Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors
Purinergic P2Y Receptor Antagonists - therapeutic use
Receptor, PAR-1 - antagonists & inhibitors
Risk Assessment
Title Novel antiplatelet drugs in clinical development
URI https://www.ncbi.nlm.nih.gov/pubmed/24108565
Volume 110
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