Temporal Interactions between Oral Irritants: Piperine, Zingerone, and Capsaicin

• Published in: Chemical senses Vol. 32; no. 5; pp. 455 - 462
• Main Authors: Affeltranger, Mark A., McBurney, Donald H., Balaban, Carey D.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.06.2007; Oxford Publishing Limited (England)
• Subjects: adaptation; Administration, Oral; Alkaloids - toxicity; Benzodioxoles - toxicity; Biological and medical sciences; capsaicin; Capsaicin - toxicity; Fundamental and applied biological sciences. Psychology; Guaiacol - analogs & derivatives; Guaiacol - toxicity; Humans; Irritants - toxicity; Olfaction. Taste; Perception; Piperidines - toxicity; piperine; Polyunsaturated Alkamides - toxicity; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; psychophysics; zingerone; adaptation; piperine; psychophysics; zingerone; capsaicin; Piperine; Psychophysics; Capsaicin; Interaction; Adaptation

Sequential presentation of 2 irritants may produce cross-sensitization or cross-adaptation effects upon introduction of the second irritant. In Experiment 1, subjects were given either 34 min of stimulation with zingerone, capsaicin, or piperine or one of those irritants for 23 min followed by blank...