Tissue-Type Plasminogen Activator Therapy Versus Primary Coronary Angioplasty: Impact on Myocardial Tissue Perfusion and Regional Function 1 Month After Uncomplicated Myocardial Infarction

• Published in: Journal of the American College of Cardiology Vol. 31; no. 2; pp. 338 - 343
• Main Authors: Agati, Luciano, Voci, Paolo, Hickle, Patrick, Vizza, Dario C., Autore, Camillo, Fedele, Francesco, Feinstein, Steven B., Dagianti, Armando
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.02.1998; Elsevier Science
• Subjects: Age Factors; Angioplasty, Balloon, Coronary; Biological and medical sciences; Cardiology. Vascular system; Cineradiography; Cohort Studies; Contrast Media - administration & dosage; Coronary Angiography; Coronary Circulation; Coronary Disease - pathology; Coronary Disease - physiopathology; Coronary heart disease; Coronary Vessels - pathology; Creatine Kinase - analysis; Echocardiography; Female; Follow-Up Studies; Heart; Heart - physiopathology; Hospitalization; Humans; Injections, Intra-Arterial; Injections, Intravenous; Male; Medical sciences; Microcirculation; Middle Aged; Myocardial Infarction - drug therapy; Myocardial Infarction - pathology; Myocardial Infarction - physiopathology; Myocardial Infarction - therapy; Myocardium - pathology; Patient Admission; Plasminogen Activators - administration & dosage; Plasminogen Activators - therapeutic use; Risk Factors; Thrombolytic Therapy; Tissue Plasminogen Activator - administration & dosage; Tissue Plasminogen Activator - therapeutic use; ACE; WMSI; TIMI; PTCA; CK; CSI; IRA; AMI; MCE; t-PA; Short term; Human; Regional perfusion; Infarct; Treatment efficiency; Size; Coronary artery; Instrumentation therapy; Cardiovascular disease; Instrumental dilatation; Coronary heart disease; Chemotherapy; Treatment; Activator; Myocardium; Plasminogen; Fibrinolytic; Comparative study

Objectives. This study sought to compare the impact of primary coronary angioplasty and thrombolytic therapy for acute myocardial infarction (AMI) on 1-month infarct size and microvascular perfusion. Background. The effect of the reperfusion strategies of primary coronary angioplasty and thrombolyti...