Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization - Liu, Zhuoming; VanBlargan, Laura A.; Bloyet, Louis-Marie; Rothlauf, Paul W.; Chen, Rita E.; Stumpf, Spencer; Zhao, Haiyan; Errico, John M.; Theel, Elitza S.; Liebeskind, Mariel J.; Alford, Brynn; Buchser, William J.; et al. (Cell host & microbe, 2021)
Keywords: ACE2 receptor decoys; Amino Acid Substitution; Angiotensin-Converting Enzyme 2 - genetics; Animals; Antibodies, Monoclonal - blood; Antibodies, Monoclonal - immunology; Antibodies, Neutralizing - immunology; Antibodies, Neutralizing - pharmacology; Antibodies, Viral - blood; Antibodies, Viral - immunology; Chlorocebus aethiops; convalescent sera; coronaviruses; COVID-19 - virology; COVID-19 vaccines; COVID-19 Vaccines - immunology; Female; Humans; Life Sciences; Mice; Mice, Inbred BALB C; Microbiology and Parasitology; Models, Molecular; monoclonal antibodies; Mutation; Neutralization Tests - methods; Protein Binding; receptor-binding domain; Receptors, Virus - metabolism; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; SARS-CoV-2 escape mutants; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Vero Cells; Virology; COVID-19 vaccines; convalescent sera; receptor-binding domain; SARS-CoV-2 escape mutants; ACE2 receptor decoys; coronaviruses; monoclonal antibodies; Antibody; SARS - CoV - 2; Virology