Identification and functional characterization of glycosyltransferase-related biomarkers for tuberculosis diagnosis

• Published in: AMB Express Vol. 15; no. 1; pp. 56 - 13
• Main Authors: Zhang, Yibiao, Ye, Xiaoyun, Xu, Jiancong, He, Jixiao, Lu, Xiaobing
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 28.03.2025; Springer Nature B.V; SpringerOpen
• Subjects: Apoptosis; Biomarkers; Biomedical and Life Sciences; Biotechnology; Diagnosis; Diagnostic markers; Effectiveness; Enrichment; Gene expression; Gene set enrichment analysis; Genes; Glycosyltransferase; Glycosyltransferase-related genes; Immune system; Infectious diseases; Life Sciences; Microbial Genetics and Genomics; Microbiology; MicroRNAs; miRNA; mRNA; Network analysis; Non-coding RNA; Original; Original Article; Potassium channels (inwardly-rectifying); Public health; Regulatory mechanisms (biology); Tuberculosis; WGCNA; Glycosyltransferase-related genes; Tuberculosis; Diagnostic markers; WGCNA

Tuberculosis (TB) is an infectious disease that presents a serious risk to public health. Glycosyltransferase-related genes (GTRGs) are instrumental in assessing the risk of latent tuberculosis infection progressing to active TB. This study aims to develop novel, accurate, and effective diagnostic m...