Cytoskeletal features of alveolar myofibroblasts and pericytes in normal human and rat lung

• Published in: The journal of histochemistry and cytochemistry Vol. 40; no. 12; pp. 1955 - 1963
• Main Authors: Kapanci, Y, Ribaux, C, Chaponnier, C, Gabbiani, G
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA Histochemical Soc 01.12.1992; SAGE Publications; Histochemical Society
• Subjects: Actins - analysis; Actins - immunology; Air breathing; Animals; Antibodies - immunology; Arterioles - cytology; Biological and medical sciences; Calcium-Binding Proteins - analysis; Calcium-Binding Proteins - immunology; Cytoskeleton - chemistry; Cytoskeleton - ultrastructure; Desmin - analysis; Desmin - immunology; Fibroblasts - cytology; Fibroblasts - ultrastructure; Fluorescent Antibody Technique; Fundamental and applied biological sciences. Psychology; Gelsolin; Humans; Lung - cytology; Lung - ultrastructure; Microfilament Proteins - analysis; Microfilament Proteins - immunology; Microscopy, Immunoelectron; Muscle, Smooth, Vascular - cytology; Muscle, Smooth, Vascular - ultrastructure; Pulmonary Alveoli - cytology; Pulmonary Alveoli - ultrastructure; Rats; Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics; Vertebrates: respiratory system; Vimentin - analysis; Vimentin - immunology; Human; Vimentin; Pericyte; Rat; Lung; Myofibroblast; Rodentia; Contractile protein; Actins; Smooth muscle; Respiratory system; Desmin; Proteins; Vertebrata; Mammalia; Pulmonary alveolus; Cytoskeleton; Interstitial

Frozen or paraffin-embedded human and rat lung specimens were stained with antibodies against total actin, alpha-smooth muscle (SM) actin, vimentin, desmin, or gelsolin. Alveolar interstitial myofibroblasts [i.e., contractile interstitial cells (CIC)] were labeled by total actin antibody but not by...