Nailfold videocapillaroscopy findings are associated with IIM subtypes and IFN activation

• Published in: Arthritis research & therapy Vol. 27; no. 1; pp. 62 - 11
• Main Authors: Tang, Mingwei, Shi, Jia, Pang, Yiyun, Zhou, Shuang, Liu, Jinjing, Wu, Chanyuan, Li, Mengtao, Zeng, Xiaofeng, Wang, Qian
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.03.2025; BioMed Central; BMC
• Subjects: Adult; Aged; Autoantibodies - blood; Autoantibodies - immunology; Autoimmune diseases; Biomarkers - blood; Capillaries - pathology; Cross-Sectional Studies; Cytokines - blood; Diagnosis; Diseases; Female; Fingernails; Health aspects; Humans; Idiopathic Inflammatory myopathy; Immunity; Inflammation; Interferon; Interferons - metabolism; Ligases; Male; Medical examination; Medical research; Medical screening; Medicine, Experimental; Microscopic Angioscopy - methods; Microscopy, Medical; Middle Aged; Muscle diseases; Myositis - blood; Myositis - diagnosis; Myositis - immunology; Myositis-specific antibody; Nailfold videocapillaroscopy; Nails - blood supply; Transfer RNA; Type I interferon; China; Nailfold videocapillaroscopy; Idiopathic Inflammatory myopathy; Type I interferon; Myositis-specific antibody

This study aimed to characterize nailfold videocapillaroscopy (NVC) features in patients with different subtypes of Idiopathic inflammatory myopathy (IIM) and to investigate the correlations between NVC findings, myositis-specific antibody (MSA) subtypes, disease activity, cytokine profiles, and int...