Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia

• Published in: Pediatrics (Evanston) Vol. 136; no. 1; p. e1
• Main Authors: Backeljauw, Barynia, Holland, Scott K, Altaye, Mekibib, Loepke, Andreas W
• Format: Journal Article
• Language: English
• Published: United States 01.07.2015
• Subjects: Adolescent; Anesthesia - methods; Brain - pathology; Child; Child, Preschool; Cognition - physiology; Cognition Disorders - diagnosis; Cognition Disorders - physiopathology; Female; Humans; Intelligence - physiology; Intelligence Tests; Language Development; Magnetic Resonance Imaging; Male; Postoperative Complications; Time Factors

Anesthetics induce widespread cell death, permanent neuronal deletion, and neurocognitive impairment in immature animals, raising substantial concerns about similar effects occurring in young children. Epidemiologic studies have been unable to sufficiently address this concern, in part due to relian...