Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia

• Published in: Psychiatry research Vol. 265; pp. 70 - 76
• Main Authors: Ma, Jie, Shang, Shanshan, Wang, Jihan, Zhang, Tianbu, Nie, Fayi, Song, Xiaobin, Heping Zhao, Zhu, Chunhui, Zhang, Rui, Hao, Dingjun
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.07.2018
• Subjects: Adult; Biomarkers - blood; Female; Gene Expression Profiling - methods; Gene Regulatory Networks - physiology; Humans; Male; MicroRNAs - blood; MicroRNAs - genetics; MiRNA; Molecular diagnosis; Real-Time Polymerase Chain Reaction - methods; Schizophrenia; Schizophrenia - blood; Schizophrenia - diagnosis; Schizophrenia - genetics; Synaptic function; Target gene; Schizophrenia; Synaptic function; Molecular diagnosis; MiRNA; Target gene

•Differentially expressed microRNAs were identified in the peripheral blood of first-onset schizophrenia patients and controls.•MiR-22-3p, miR-92a-3p, and miR-137 could be used in combination as a biomarker for schizophrenia.•The target genes of miR-22-3p, miR-92a-3p, and miR-137 are associated with...