Biochemical and Structural Properties of a Thermostable Mercuric Ion Reductase from Metallosphaera sedula

• Published in: Frontiers in bioengineering and biotechnology Vol. 3; p. 97
• Main Authors: Artz, Jacob H, White, Spencer N, Zadvornyy, Oleg A, Fugate, Corey J, Hicks, Danny, Gauss, George H, Posewitz, Matthew C, Boyd, Eric S, Peters, John W
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 01.01.2015; Frontiers Media S.A
• Subjects: BASIC BIOLOGICAL SCIENCES; Bioengineering and Biotechnology; biosensor; merA; mercuric reductase; mercuric reductase, mercury detoxification, thermophile, thermostability, structure, biosensor, MerA; Structure; thermophile; thermostability; mercury detoxification; MerA; biosensor; thermostability; mercuric reductase; structure; thermophile

Mercuric ion reductase (MerA), a mercury detoxification enzyme, has been tuned by evolution to have high specificity for mercuric ions (Hg(2+)) and to catalyze their reduction to a more volatile, less toxic elemental form. Here, we present a biochemical and structural characterization of MerA from t...