The Zinc Finger Transcription Factor Zbtb7b Represses CD8-Lineage Gene Expression in Peripheral CD4 + T Cells

How CD4-CD8 differentiation is maintained in mature T cells is largely unknown. The present study has examined the role in this process of the zinc finger protein Zbtb7b, a critical factor for the commitment of MHC II-restricted thymocytes to the CD4 + lineage. We showed that Zbtb7b acted in periphe...

Full description

Saved in:
Bibliographic Details
Published inImmunity (Cambridge, Mass.) Vol. 29; no. 6; pp. 876 - 887
Main Authors Wang, Lie, Wildt, Kathryn F., Castro, Ehydel, Xiong, Yumei, Feigenbaum, Lionel, Tessarollo, Lino, Bosselut, Rémy
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 19.12.2008
Elsevier Limited
Subjects
Online AccessGet full text

Cover

Loading…