The Prognostic Relevance of MRI Characteristics in Myxofibrosarcoma Patients Treated with Neoadjuvant Radiotherapy

• Published in: Cancers Vol. 15; no. 10; p. 2843
• Main Authors: van Ravensteijn, Stefan G, Nederkoorn, Maikel J L, Wal, Tom C P, Versleijen-Jonkers, Yvonne M H, Braam, Pètra M, Flucke, Uta E, Bonenkamp, Johannes J, Schreuder, Bart H W, van Herpen, Carla M L, de Wilt, Johannes H W, Desar, Ingrid M E, de Rooy, Jacky W J
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.05.2023; MDPI
• Subjects: Edema; Growth patterns; Magnetic resonance imaging; Medical prognosis; Metastasis; Patients; Radiation therapy; Radiotherapy; Sarcoma; Surgery; Survival; Tails; Tumors; Netherlands; magnetic resonance imaging; vascular pedicle; myxofibrosarcoma; neoadjuvant radiotherapy; local recurrence; prognostic factors; tail sign; soft tissue sarcoma

To improve local control, neoadjuvant radiotherapy (nRT) followed by surgery is the standard of care in myxofibrosarcoma (MFS) because of its infiltrative growth pattern. Nevertheless, local recurrence rates are high. Data on prognostic factors for poor clinical outcomes are lacking. This retrospect...