Clinical outcomes with on-label and off-label use of the transcatheter heart valve in the United States

• Published in: Catheterization and cardiovascular interventions Vol. 84; no. 1; pp. 124 - 128
• Main Authors: Lardizabal, Joel A., Macon, Conrad J., O'Neill, Brian P., Singh, Vikas, Martinez, Claudia A., Alfonso, Carlos, Cohen, Mauricio G., Williams, Donald B., O'Neill, William W., Heldman, Alan W.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.07.2014; Wiley Subscription Services, Inc
• Subjects: Aged, 80 and over; Aortic stenosis; Aortic valve; Aortic Valve Stenosis - mortality; Aortic Valve Stenosis - surgery; Cause of Death - trends; Clinical outcomes; Female; Follow-Up Studies; Heart Valve Prosthesis; Humans; Male; Mortality; Patients; Prospective Studies; Risk Assessment; Risk Factors; Stenosis; structural heart intervention; Survival Rate - trends; Transcatheter Aortic Valve Replacement - methods; Treatment Outcome; United States - epidemiology; valvular heart disease; United States; structural heart intervention; valvular heart disease; aortic stenosis

Objective We explored the efficacy, safety, and clinical consequences of on‐label and off‐label transcatheter aortic valve replacement (TAVR) in the real‐world setting. Background The transcatheter heart valve (THV) was initially approved only for transfemoral (TF) delivery (on‐label use) during TAV...