C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression - Xu, Gui‐lian; Chen, Jian; Yang, Fei; Li, Gui‐qing; Zheng, Li‐xin; Wu, Yu‐zhang (Hepatology (Baltimore, Md.), 2014)
Keywords: Acute Disease; Animals; Complement C5a - immunology; Complement C5a - metabolism; Female; Fibrinogen - immunology; Fibrinogen - metabolism; Hepatitis; Hepatitis, Viral, Animal - immunology; Hepatitis, Viral, Animal - metabolism; Hepatology; Humans; Liver Failure, Acute - immunology; Liver Failure, Acute - metabolism; MAP Kinase Signaling System - immunology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mortality; Murine hepatitis virus - immunology; Murine hepatitis virus - metabolism; Pathogenesis; Receptor, Anaphylatoxin C5a - genetics; Receptor, Anaphylatoxin C5a - immunology; Receptor, Anaphylatoxin C5a - metabolism; Severity of Illness Index; Up-Regulation - immunology; Viral infections