Effect of cytochrome P450 3A5 genotype on atorvastatin pharmacokinetics and its interaction with clarithromycin - Shin, Jaekyu; Pauly, Daniel F; Pacanowski, Michael A; Langaee, Taimour; Frye, Reginald F; Johnson, Julie A (Pharmacotherapy, 2011)
Keywords: Adult; Alleles; Atorvastatin Calcium; Clarithromycin - blood; Clarithromycin - pharmacology; Cytochrome P-450 CYP3A - genetics; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Genotype; Heptanoic Acids - administration & dosage; Heptanoic Acids - blood; Heptanoic Acids - chemistry; Heptanoic Acids - pharmacokinetics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage; Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood; Hydroxymethylglutaryl-CoA Reductase Inhibitors - chemistry; Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics; Male; Prospective Studies; Pyrroles - administration & dosage; Pyrroles - blood; Pyrroles - chemistry; Pyrroles - pharmacokinetics; Young Adult