Cancer nanomedicines: So many papers and so few drugs

• Published in: Advanced drug delivery reviews Vol. 65; no. 1; pp. 80 - 88
• Main Authors: Venditto, Vincent J., Szoka, Francis C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2013
• Subjects: Antineoplastic Agents - administration & dosage; Antineoplastic Agents - chemistry; Antitumor agents; Camptothecin; Drug Carriers - administration & dosage; Drug Carriers - chemistry; Drug Delivery Systems - methods; Humans; Liposomes; Monoclonal antibodies; Nanomedicine - methods; Neoplasms - drug therapy; Platinum therapy; Polymers; Monoclonal antibodies; Camptothecin; Liposomes; Platinum therapy; Polymers

This review identifies a timeline to nanomedicine anticancer drug approval using the business model of inventors, innovators and imitators. By evaluating the publication record of nanomedicine cancer therapeutics we identified a trend of very few publications prior to FDA approval. We first enumerat...